08.13 - Blood Flow, Ventilation-Perfusion (Leffler) - Question Flashcards Preview

Pulmonology > 08.13 - Blood Flow, Ventilation-Perfusion (Leffler) - Question > Flashcards

Flashcards in 08.13 - Blood Flow, Ventilation-Perfusion (Leffler) - Question Deck (28)
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1
Q

Ratio of change in pressure to change in blood flow in pulmonary circulation

A

Greater than 1:1 –> Blood flow change is more than pressure change causing it

2
Q

Blood flow in base vs apex

A

Blood flow increases from apex to base of lungs

3
Q

Vascular resistance in base vs apex of lung

A

Vascular resistance decreases from apex to base

4
Q

Pressure in base vs apex of lung

A

Pressure increases; Pressure drop increases from apex to base

5
Q

PA vs Pa vs Pv in top third of lung

A

PA>Pa>Pv

6
Q

PA vs Pa vs Pv in middle third of lung

A

Pa>PA>Pv

7
Q

PA vs Pa vs Pv in bottom third of lung

A

Pa>Pv>PA

8
Q

Blood pressure in base vs apex

A

Blood Pressure increases from apex to base

9
Q

Where does fluid move out of lungs?

A

Where pressure is highest –> Base of lungs –> Edema in CHF

10
Q

Which part of lung becomes edematous in CHF

A

Base, highest pressure

11
Q

Lung arteries and arterioles constrict in response to

A

Hypoxia, Hypercapnia, Acidosis

12
Q

Effect of Hypoxia on Lung arteries and arterioles

A

Constrict

13
Q

Effect of Hypercapnia on Lung arteries and arterioles

A

Constrict

14
Q

Cause of chronic pulmonary hypertension

A

Hypoxia –> Increased Pulmonary Vascular Resistance

15
Q

VA/Q ___ from lung apex to base

A

decreases

16
Q

The greater the VA/Q, the ___ the O2, and the __ the CO2

A

Higher O2, Lower CO2

17
Q

Compliance at top of lung vs bottom

A

Lower compliance at top –> Less change in volume for given change in pressure

18
Q

Which part of lung has highest compliance

A

Bottom –> Greater change in volume for given change in pressure

19
Q

Change in VA/Q from bottom to top of lung

A

Increase

20
Q

Change in Q and VA from base to apex of lung

A

Both decrease, but Q decreases more rapidly

21
Q

Which part of lung has highest partial pressure of O2

A

Top –> Hyperventilated –> Blood flow much lower than ventilation

22
Q

Which part of lung has lowest partial pressure of O2

A

Base –> Hypoventilated

23
Q

Which part of lung has higher partial pressure of CO2

A

Base

24
Q

Hypoperfused by normally ventilated =

A

High PO2

25
Q

Hypoventilated by normally perfused =

A

Low PO2

26
Q

T/F: VA/Q mismatch or shunt can both increase PaCO2

A

False, neither

27
Q

T/F: Hypoxemia can be caused by VA/Q mismatch

A

TRUE

28
Q

T/F: Hypoxemia can be caused by Shunt

A

TRUE

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