11- Anticholenerestase Agents Flashcards Preview

Pharm > 11- Anticholenerestase Agents > Flashcards

Flashcards in 11- Anticholenerestase Agents Deck (16)
Loading flashcards...
1
Q

AChE actions

A

Break down ACh at the synapse

2
Q

Where are Ach actions mediated by musc. Receptors

A

CNS

Viseral organs

3
Q

BuChE examples

A

Aspirin
Cocaine
Heroine

4
Q

Function of BuChE

A

Break down ACh

5
Q

What are anti cholinesterase classifications based on

A

Duration of enzyme inhibition

6
Q

Effect of anti-cholinesterase

A

Inhibit AChE
Intensify ACh
Increased parasympathetic

7
Q

Therapeutic use of reversible anti-AChE receptors

A

Relief from glaucoma
GI stimulant
Diagnostic for myasthenia gravis
Anti parasitic

8
Q

Contraindications for anti AChE

A

Food animal
Severely sick animal
Respiratory issues
Pregnant

9
Q

Edrophonium

A

Short acting
Not hydrolyzed by AChE
Muscle relaxant

10
Q

Dose for Edrophonium

A

Dog:.1-.2 mg/kg
Cat: .5-1 mg/kg

11
Q

Neostigmine

A

Intermediate duration
Hydrolyzed by AChE
Does not cross bbb

12
Q

Actions of Neostigmine

A

Glaucoma
Treatment for m gravis
GI stimulant
Reversal for muscle relaxant

13
Q

Physostigmine

A

Greater CNS actions

Similar to Neostigmine

14
Q

Parathion main uses

A

Agricultural

  • insecticide
  • mosquitos control
  • cattle dip
15
Q

Treatment of OP poisoning

A

Praladoxime

16
Q

OP poisoning

A

Inhaled: ocular, respiratory
Oral: GI, systemic
Cutaneous: sweating, muscle issues