24 - Endometrial Cancer

Question 1

what is type 1 EC?

Answer 1

Endometrioid adenocarcinoma

Question 2

what is type 2 EC?

Answer 2

Uterine serous & clear cell carcinoma

Question 3

is type 1/ 2 EC more common?

Answer 3

type 1

Question 4

which type of EC is more high grade, more aggressive, worse prognosis?

Answer 4

type 2

Question 5

who is mostly affected by type 2 EC?

Answer 5

older woman

Question 6

how is EC staged?

Answer 6

using MRI -

depth of myometrial invasion
cervical involvement
lymph node involvement

Question 7

what are the stages of EC according to FIGO?

Answer 7

1A, 1B, 2, 3A, 3B, 3C, 4

Question 8

treatment of early stage EC?

Answer 8

surgery TAH/BSO/washings

Question 9

treatment of high risk histology EC?

Answer 9

chemotherapy

Question 10

treatment of advanced stage EC?

Answer 10

radiotherapy

Question 11

palliation treatment of EC?

Answer 11

progesterone

Question 12

RFs for endometrial cancer?

Answer 12

post-menopausal women

obesity

PCOS

Endometrial hyperplasia with atypia

HNPCC/Lynch type II familial cancer syndrome

Question 13

2 symptoms of EC?

Answer 13

abnormal vaginal bleeding

Post menopausal bleeding

Question 14

diagnosis of EC?

Answer 14

histology of endometrium

Question 15

main treatment of EC?

Answer 15

Total Abdominal Hysterectomy with removal of tubes and ovaries and peritoneal washings

Question 16

which scan is used to look at suspected EC?

Answer 16

Trans-vaginal scan - to look at endometrial thickness and contour