3.9 - Carboxylic Acids 2

Question 1

Name of Mechanism: Reaction of Acyl Chlorides with Ammonia

Answer 1

Nucleophilic Addition-Elimination

Question 2

Name of Mechanism: Hydrolysis of Acyl Chlorides

Answer 2

Nucleophilic Addition-Elimination

Question 3

Name of Mechanism: Reaction of Acyl Chlorides with Ammonia

Answer 3

Nucleophilic Addition-Elimination

Question 4

Name of Mechanism: Reaction of Acyl Chlorides to form Amides

Answer 4

Nucleophilic Addition-Elimination

Question 5

What does a Double-headed curly arrow show?

Answer 5

The Movement of a Pair of Electrons

Question 6

What is an Acyl group?

Answer 6

R-C=O

Question 7

Define: Nucleophile

Answer 7

Electron Pair Donor

Question 8

General Equation: Hydrolysis of Acyl Chlorides

Answer 8

R-C(=O)-Cl +H₂O |> R-C(=O)-OH + HCl

Question 9

General Equation: Reaction of Acyl Chlorides with Alcohol

Answer 9

RCOCl + R’OH |> RCOOR’ + HCl

Question 10

General Equation: Reaction of Acyl Chlorides to form Amides

Answer 10

RCOCl + 2R’NH₂ |> R-C(=O)-NH-R’ + R’NH₃⁺Cl⁻

Question 11

General Equation: Hydrolysis of Acid Anhydrides

Answer 11

R-C(=O)-O-C(=O)-R + H₂O |> 2R-C(=O)-OH

Question 12

General Equation: Reaction of Acyl Chlorides with Ammonia

Answer 12

RCOCl + 2NH₃ |> R-C(=O)-NH₂ + NH₄Cl

Question 13

Reagent: Reaction of Acyl Chlorides to form Amides

Answer 13

R’NH₂

Question 14

Reagent: Reaction of Acyl Chlorides with Ammonia

Answer 14

NH₃

Question 15

Reagent: Hydrolysis of Acid Anhydrides

Answer 15

H₂O

Question 16

Product: Hydrolysis of Acid Anhydrides

Answer 16

Carboxylic Acid

Question 17

Reagent: Hydrolysis of Acyl Chlorides

Answer 17

H₂O

Question 18

Carbonyl bond of the Acid Derivative is ____ ?

Answer 18

Polar

Question 19

Acid Derivatives are more ____ than Carboxylic Acids?

Answer 19

Reactive