5: Skin structure & function 3 Flashcards Preview

Dermatology Week 1 2017/18 > 5: Skin structure & function 3 > Flashcards

Flashcards in 5: Skin structure & function 3 Deck (22)
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1
Q

Which structure joins the epidermis and the dermis?

A

Dermo-epidermal junction (DEJ)

2
Q

What are the two layers of the dermo-epidermal junction?

A

Lamina lucida

Lamina densa

comprised of connective tissue

3
Q

What are the main cell types found in the dermis?

A

Fibroblasts

Immune cells - macrophages, mast cells, lymphocytes, Langerhans cells

4
Q

Which types of connective tissue fibres are found in the dermis?

A

Collagen

Elastin

5
Q

How does blood reach the dermis?

A

Superficial and deep vascular plexuses

6
Q

What are benign vascular endothelial tumours called?

A

Angiomas

7
Q

Apart from arterioles and venules, what other vessels are found in the dermis?

A

Lymphatic vessels

8
Q

Which cells take antigens to lymphatics in the dermis?

A

Langerhans cells

Lymphocytes

9
Q

If lymphatic vessels are damaged, what symptom can present?

A

Lymphoedema

10
Q

Which type of nerve provides feeling for the dermis?

A

Somatic sensory nerves

11
Q

What are Pacinian corpuscles responsible for sensing?

A

Vibration

(23/12 - P is not for pressure, it turns out)

12
Q

What are Meissner’s corpuscles responsible for sensing?

A

Pressure

Light touch

13
Q

Apart from somatic sensory nerves, which other type of nerves supply blood vessels, nerves and glands in the dermis?

A

Autonomic nerves - sympathetic and parasympathetic

14
Q

What do Pacinian corpuscles look like under the microscope?

A

Onions

15
Q

What is a benign nerve tumour of the skin called?

A

Neurofibroma

16
Q

Which genetic skin condition sees the development of loads of neurofibromas all over the back and other surfaces?

A

Neurofibromatosis Type 1

17
Q

What are the three types of glands found in the skin?

A

Sebaceous glands

Apocrine glands

Eccrine glands

18
Q

What is the function of sebaceous glands?

A

Secrete sebum into the pilary canal to lubricate hairs and protect from fungal infection

19
Q

What skin disease involves blocking of pilary canals by excess sebum +/- bacterial colonisation?

A

Acne

20
Q

What is the function of apocrine glands and where are they found?

A

Produce oily, odorous fluid

Found in the axillae and perineum

21
Q

What is the function of eccrine glands and where in particular are they found?

A

Secrete sweat to cool body by evaporation and moisten palms/soles

Found everywhere, but palms, soles and axillae in particular

22
Q

Which autonomic nerves supply eccrine glands?

A

Sympathetic nerves