[7] Pharmacology of Immunization Flashcards Preview

[THER 201] 3rd Lecture Exam > [7] Pharmacology of Immunization > Flashcards

Flashcards in [7] Pharmacology of Immunization Deck (36)
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1
Q

First evidence of vaccination came from? What disease was it?

A

Egypt

Smallpox

2
Q

Who introduced alternative inoculation with cowpox?

A

Edward Jenner

3
Q

The last known natural case of Variola was in?

A

Somalia (Pirates bang bang bullet bullet gun)

4
Q

Are anti-vaccination people stupid?

A

Yes, I hope they get smallpox in Somalia.

5
Q

Function: CD8+ T Cells

A

Directly kill infected cells

6
Q

Function: CD4+ T Cells

A

Support activation and differentiation of B Cells, CD8+ T Cells and Macrophages

7
Q

Define: Community Herd Immunity

A

When a critical portion of a community is immunized, most members are protected against the disease because there is little opportunity for an outbreak

8
Q

[Classification of Vaccine]

BCG

A

Live Attenuated Vaccine

9
Q

[Classification of Vaccine]

MMR

A

Live Attenuated Vaccine

10
Q

[Classification of Vaccine]

Tetanus Immune Globulin

A

Immune Globulins

11
Q

[Classification of Vaccine]

Yellow Fever

A

Live Attenuated Vaccine

12
Q

[Classification of Vaccine]

Polio

A

Inactivated Vaccine

13
Q

[Classification of Vaccine]

Typhoid

A

Inactivated Vaccine

14
Q

[Classification of Vaccine]

Rabies

A

Inactivated Vaccine

15
Q

[Classification of Vaccine]

Diphtheria

A

Toxoid

16
Q

[Classification of Vaccine]

Pertussis

A

Kiled

17
Q

[Classification of Vaccine]

Tetanus

A

Toxoid

18
Q

[Vaccination Route]

Tetanus, Diphtheria, Pertussis Vaccine

A

IM

19
Q

[Vaccination Route]

Hepatitis B

A

IM

20
Q

[Vaccination Route]

Varicella

A

Subcutaneous

21
Q

[Vaccination Route]

MMR

A

Subcutaneous

22
Q

[Classification of Vaccine]

Hepatitis B

A

Inactivated Vaccine

23
Q

[Vaccination Route]

Pneumococcal Vaccine

A

IM

24
Q

[Classification of Vaccine]

Pneumococcal Vaccine

A

Inactivated Vaccine

25
Q

[Vaccination Route]

Influenza Vaccine

A

Inactivated Vaccine

26
Q

[Classification of Vaccine]

Influenza Vaccine

A

IM

27
Q

Which statement does not apply to live vaccines?
A. Severe reactions are possible
B. May produce effective immunity
C. Composed of fractional and subunit vaccines
D. Vaccines are fragile and must be stored and
handled carefully

A

C

28
Q
Which vaccine is used for Passive immunization? 
A. Measles vaccine
B. BCG
C. Tetanus immunoglobulin
D. Rabies vaccine
A

C

29
Q

Which statement DOES NOT apply to inactivated vaccines?
A. Components do not replicate
B. Less interference from circulating antibody than live vaccines
C. Generally require only 1 dose to induce immunity
D. Immune response is mostly humoral

A

C

30
Q
Contraindications to administration of live vaccines are the ff. EXCEPT:
A. Allergy to antigen in the vaccines 
B. Pregnancy
C. Immunosupression
D. Cough and colds
A

D

31
Q

Which statement does not apply to pre polysaccharide vaccines?
A. It gives adequate protection in patients less than 2 years old.
B. It does not have a booster response
C. It produces antibodies with less functional activity
D. It is an inactivated vaccine

A

A

32
Q
Which vaccine is not included in the present expanded program of immunization in the Philippines?
A. BCG
B. Hepatitis B Vaccine 
C. Measles vaccine 
D. Typhoid vaccine
A

D

33
Q

Which statement is FALSE about live attenuated vaccines?
A. The protection from the vaccine is immediate within one day of giving the vaccine
B. The live virus or bacteria must replicate in order to produce immunity
C. Symptoms of the disease may occur but are mild
D. None of the above

A

A

34
Q

The following vaccines are recommended for health care personnel EXCEPT:
A. Hepatitis B vaccine
B. Influenza vaccine
C. Tetanus, Diphtheria, Pertussis vaccine
D. Rotavirus vaccine

A

D

35
Q
Contraindications to administration of inactivated vaccines are the following EXCEPT:
A. Encephalopathy 
B. Allergy to antigen 
C. Low grade fever 
D. None of the above
A

C

36
Q

Which statement is FALSE about inactivated vaccines?
A. Components in the vaccine do not replicate
B. The antibody titers versus the antigen diminishes with time
C. One dose usually induces immunity
D. The inactivated vaccines are generally less effective than live vaccines

A

C