8: Viral Diseases - Yoho

Question 1

causes verruca

Answer 1

human papova virus

Question 2

replication of HPV

Answer 2

• requires a host for survival
• multiplies w/i epidermal cell nucleus
• NOT dermis
• incubation period

Question 3

key feature verruca

Answer 3

loss of skin lines

Question 4

thickness of dermis in soles

Answer 4

1.5 mm

Question 5

virus verruca vulgaris/common warts

Answer 5

HPV 2 & 4

Question 6

grey or brown papules with keratinized pitted surface

frequently multiple, up to 2 cm

Answer 6

verruca vulgaris

Question 7

virus verruca plana

Answer 7

HPV 3 & 10

Question 8

small flat lesions with koebnerization

Answer 8

verruca plana

Question 9

koeberization

Answer 9

scratch the lesion, spread the virus along lines of scratching

Question 10

virus filiform or digitate warts

Answer 10

HPV 6 & 11

Question 11

finger-like projections froma single base that bleed easily

Answer 11

filiform or digitate warts

Question 12

virus plantar warts/verruca plantaris

Answer 12

HPV 1 and mosaic HPV 2

Question 13

*** pain on side to side pressure on lesion on bottom of foot

Answer 13

verruca plantaris

Question 14

histopathology of verruca

Answer 14

• epidermal hyperplasia
• inclusion bodies (psuh nucleus to side)
• papillomatosis (above skin level)

Question 15

virus molluscum contagiosum

Answer 15

DNA pox virus (poxviridae)

Question 16

dome shaped papules with central umbilification

pearly white or translucent

Answer 16

molluscum contagiosum

Question 17

tzanck test molluscum contagiosum

Answer 17

ground glass inclusion bodies

• a KOH wet moutn will show molluscum bodies

Question 18

two forms of herpes simplex on foot =

Answer 18

herpetic whitlow (dentist - under toe nail)

eczema herpeticum (compromised skin)

Question 19

non genital v. genital HSV

Answer 19

nongenital - HSV 1

genital - HSV 2

Question 20

sudden onset itching and burning, small grouped vesicles on erythematous base, painful

Answer 20

herpes simplex

Question 21

histopathology herpes simplex

Answer 21

ballooning degeneration, acantholysis, large multi-nucleated cells

Question 22

topical and oral tx herpes simplex

Answer 22

topical - acyclovir, penciclovir

oral - acyclovir, famciclovir, valacyclovir

Question 23

shingles virus

Answer 23

varicella virus

Question 24

pain localized in area of dermatome followed 2-5 d later by erythematous papules

Answer 24

herpes zoster

Question 25

hand, foot and mouth disease virus

Answer 25

coxsackie virus A16 and A5

Question 26

flu like symptoms before acute vesicular eruption in children, late summer

light grey vesicles in red areola, painful

Answer 26

hand, foot, and mouth disease (location)