[A] 1.43 Organisation, demarcation Flashcards Preview

Pathology A - General Pathology > [A] 1.43 Organisation, demarcation > Flashcards

Flashcards in [A] 1.43 Organisation, demarcation Deck (11)
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1
Q

Direct forms of repair

A
  • Organisation
  • Demarcation
  • Hypotypia
  • Heteromorphosis
  • Hyperregeneration & Hypermorphosis
2
Q

Hypotypia

A

Original cells, but not the original structure

3
Q

Heteromorphosis

A

Instead of original cells, other (not connective tissue) types of cells

4
Q

Hyperregeneration & hypermorphosis

A

Fill the area but continue proliferation

5
Q

Summarise organisation

A
  • Supplementation with the original tissue
  • But with collagenous fibrous connective tissue
6
Q

Organisation occurs when…

A

Tissue loss is too large

7
Q

Organisation: Steps of the process

A
  1. Histolysis, resorption & removal
  2. New blood vessels
  3. Fibroblast differentiation (granulation tissue)
8
Q

Granulation tissue formation timeline

A
  1. First fibroblasts (2-3 days)
  2. Collagen fibres (5-7 days)
  3. Elastic fibres (4 weeks)
9
Q

Angiofibroblast tissue

A
  1. Fibroblast proliferation & collagen fibres
  2. Angiogenesis (capillary loops)
  3. Maturation & differentiation
10
Q

Maturation of the granulation tissue

A
  1. Rich in cells
  2. Poor in cells
  3. Fibre production
  4. Mature collagen fibrous connective tissue
  5. Shrinking of the tissue
  6. Scar (cictrix) formation
    • Brain = Glial scar
    • Bone = Callus
11
Q

Demarcation

A

Basically the same as organisation

  • Connective tissue encircles the area
  • Necrotised tissue dries
  • Secondary calcification might occur

Heterolysis

  • Surrounding material fluidise
  • Sequestration

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