[A] 1.52 Proliferative processes during inflammation. Flashcards Preview

Pathology A - General Pathology > [A] 1.52 Proliferative processes during inflammation. > Flashcards

Flashcards in [A] 1.52 Proliferative processes during inflammation. Deck (7)
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1
Q

Fibrosis

A

Production of excessive fibrous connective tissue in an organ or tissue as a means of repair.

Rather than as a normal constituent of an organ or tissue

2
Q

Angiogenesis: Physiological & pathological occurances

A

Physiological in adults:

  • Ovarian cycle
  • Wound healing

Pathological processes:

  • Chronic inflammation
  • Tumour induced angiogenesis
3
Q

Give the most important factors inducing angiogenesis

A
  • Vascular endothelial growth factor (VEGF)
  • Fibroblast growth factor (FGF)
4
Q

Angiogenesis in chronic inflammation: Major sources of pro-angiogenic factors

A
  • Monocytes
  • Lymphocytes
  • Macrophages
  • Mast cells
  • Platelets
5
Q

Angiogenesis in cancer: Major sources of pro-angiogenic factors

A
  • Tumour cells
  • Infiltrating leukocytes
6
Q

Pathological types of chronic inflammation

A
  1. Chronic inactive
  2. Chronic active
  3. Granulomas
  4. Pyogranulomas
7
Q

Chronic active inflammation

A

In the granulation tissue with exsudation, _neutrophil granulocyte_s, macrophage activation

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