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Individual Drugs > ADENOSINE (Adenocard®) > Flashcards

ADENOSINE (Adenocard®) Flashcards

1
Q

Generic/Trade

ADENOSINE

A

Adenocard®

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2
Q

Trade/Generic

Adenocard®

A

ADENOSINE

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3
Q

ADENOSINE (Adenocard®)

Drug Classification:

A
  • Antidysrhythmic (Class V)
  • Nucleoside
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4
Q

ADENOSINE (Adenocard®)

Mechanism of Action:

A

Adenosine (A1) R-agonist ⇒ Slows AV conduction by activation of G-protein second messengers, decreasing cAMP and inhibiting calcium entry into the
pacemaker cells

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5
Q

ADENOSINE (Adenocard®)

Pharmacokinetics

A

Onset of Action = Immediate

Peak Effects = Immediate

Duration of Effect = 30-45 seconds

Half-Life = 6 seconds

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6
Q

ADENOSINE (Adenocard®)

Indications/Field Use:

A
  • SVT (PSVT) / Narrow Complex Tachycardia
  • R/O SVT when diagnosing or assessing a rapid rhythm
  • Wide complex tachycardia
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7
Q

ADENOSINE (Adenocard®)

Contraindications:

A
  • 2°/3° Heart Block, Sick Sinus Syndrome
  • Poison/chemical induced SVT (i.e. cocaine)
  • Caution w/ asthma, bronchospasm, and unstable angina
  • Torsades de Pointes (Polymorphic Ventricular Tachycardia)
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8
Q

ADENOSINE (Adenocard®)

Side Effects/Adverse Reactions:

A

Facial flushing, HA, chest pain, dizziness

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9
Q

ADENOSINE (Adenocard®)

ADULT DOSE:

A

1st dose - 6mg rapid IVP followed by 20cc NS flush

2nd dose - 12mg rapid IVP followed by 20cc NS flush

3rd dose - 12mg rapid IVP followed by 20cc NS flush

Drug-Drug Interaction

* Methylxanthines (i.e. caffeine) are nonspecific competitive antagonists for adenosine receptors **double** the dose for Pt.’s taking large amounts* * Carbamazepines (i.e. Tegretol, Phenobarbitol) potentiate effects of adenosine –**halve** the dose*
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10
Q

ADENOSINE (Adenocard®)

PEDI DOSE:

A

1st dose - 0.1mg/kg IV/IO rapid push, max dose 6mg

2nd dose - 0.2mg/kg IV/IO rapid push, max dose 12mg

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11
Q

ADENOSINE (Adenocard®)

Precautions:

A
  • Begin printing rhythm strip before administering adenosine
  • Give in A/C or higher (more proximal)
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12
Q

ADENOSINE (Adenocard®)

Drug-Drug Interactions:

A
  • Methylxanthines (i.e. caffeine) are nonspecific competitive antagonists for adenosine receptors
  • double the dose for Pt.’s taking large amounts
  • Carbamazepines (i.e. Tegretol, Phenobarbitol) potentiate effects of adenosine –halve the dose
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Individual Drugs (37 decks)

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