Andrews Chapter 8: CTD Flashcards Preview

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Flashcards in Andrews Chapter 8: CTD Deck (13)
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1
Q

Bullous Lupus vs EBA

A

both collagen VII anti; but bullous lupus responds to dapsone. Also HLA-DR2 assox

2
Q

Chronic LE

A

DLE,
hypertrophic LE
LE-LP overlap
chilblain lupus (nose, ears, fingers, heel/calf)
tumid lupus (lots of mucin, can look like reticular erythematous mucinosis)
lupus panniculitis (vs pannic-like CTCL)

3
Q

Childhood DLE

A

More like to have SLE, less photosensitivity

4
Q

Drug that causes SLE, and drug that causes drug-induced SLE

A

etanercept and penicillamine; hydralazine, procainamide, minocycline, sulfonamide, PCN, isoniazid, anticonvulsant

5
Q

Sneddon syndrome

A

livedoid vasculopathy with CNS sx - from hyalinizing vasculopathy

6
Q

ANA in LE

A

peripheral = renal; particulate = SCLE; homogenous = histone

7
Q

Drug that can cause DM like eruption

A

Hydroxyurea

8
Q

acrodermatitis chronica atrophicans

A

progressive skin fibrosis, late stage lyme disease

9
Q

Scleroderma has loss of CD34 dermal cells, but this has increased CD34 cells

A

Nephrogenic systemic fibrosis

10
Q

Interstitial granulomatous dermatitis -describe clinical findings

A

rope sign - cord from upper back to axille; round to oval erythematous or violaceous plaques on flanks, axillae, inner thighs, abdomen, may be a/w autoimmune dz; vs GA - lesions on hands/feet/back

11
Q

Palisaded neutrophilic granulomatous dermatitis, associated with what?

A

associated with RA, SLE

12
Q

Blau syndrome

A

granulomatous disease with symmetric arthritis and uveitis; CARDS15/NOD2 mutation; early onset sarcoidosis?

13
Q

linear for of atrophoderma of pasini and pierni

A

atrophoderma of moulin