Anemia

Question 1

Common anemia signs

Answer 1

pale skin, jaundice, FATIGUE, tachycardia, breathlessness

Question 2

How you get anemia

Answer 2

lose, destroy, make too little

Question 3

most important cause iron-def. anemia

Answer 3

GI bleed

Question 4

cell size and hemoglobin in iron-def. anemia

Answer 4

small, lacking hemoglobin

Question 5

anisocytosis

Answer 5

variation in cell size in IDA

Question 6

poikilocytosis

Answer 6

funny shape cells in IDA

Question 7

of globin chains and heme molecules

Answer 7

4

Question 8

2 ways to store iron

Answer 8

ferritin, hemosiderin

Question 9

physical signs of iron def. anemia

Answer 9

pale, spoon nails, smooth tongue

Question 10

Decrease in this cofactor causes Megaloblastic anemia

Answer 10

B12/folate

Question 11

Describe Megaloblastic anemia

Answer 11

Defective DNA synthesis with macrocytic anemia

Question 12

Causes of B12 def.

Answer 12

Diet, lack intrinsic factor, pancreas damage, ileal damage, tapeworm

Question 13

Cause of chronic hemolytic anemia

Answer 13

congenital

Question 14

lab values that point to hemolytic anemia

Answer 14

increased RBC destruction and production

Question 15

Best test for hemolytic anemia

Answer 15

Direct antiglobulin test -then it is an immune process

Question 16

describe Direct antiglobulin test (DAT) also called Coombs

Answer 16

pt. blood s mixed with AHG(Coombs reagent) if they clump it is positive

Question 17

Pearls about Spherocytosis

Answer 17

Lots of spherocytes, spectrin defect, cured by splenectomy

Question 18

common crisis that can bring on spherocytosis

Answer 18

parvovirus (wipes out red cell precursors)