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Neuro Block 5-RG > Anesthesia > Flashcards

Flashcards in Anesthesia Deck (18)
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1
Q

Dalton’s law

A

total pressure = sum of partial pressures

2
Q

Henry’s law

A

solubility of gas/vapor in liquid before equilibrium is reached is determined by the partial pressure

3
Q

How are vapor anesthetics taken out of the body?

A

breathed out

4
Q

Drugs that are more soluble in the blood require more/less drug to achieve the desired effect

A

more

5
Q

How do inhalation anesthetics work mechanistically?

A

alter membrane fluidity

6
Q

Minimum alveolar concentration

A

analogous to ED50, should use 1.3-1.5x this amount

7
Q

Drugs are are more lipid soluble are more/less potent

A

more (cross membrane)

8
Q

Second gas effect

A

rapid uptake of first anesthetic from alevoli into blood creates a negative pressure in alveoli, increasing potency of second anesthetic

9
Q

What are the problems with halogenated anesthetics?

A

damage to kidneys, liver, and reproductive organs

10
Q

Why does the OR need to be so well ventilated?

A

to keep surgical team safe from gasses

11
Q

Injectable anesthetics are used

A

for induction

12
Q

Halothane, isoflurane, desflurane, sevoflurane, N2O

A

inhalation anesthetics

13
Q

Pentobarbital

  • mechanism
  • class
  • function in anesthesia
A
  • GABA agonist
  • barbituates
  • quick induction
14
Q

Methohexital

  • mechanism
  • class
  • function in anesthesia
A
  • GABA agonist
  • barbituates
  • quick induction
15
Q

Midazolam

  • mechanism
  • class
  • function in anesthesia
A
  • GABA agonist
  • benzos
  • amnesia
16
Q

Diazepam

  • mechanism
  • class
  • function in anesthesia
A
  • GABA agnonist
  • benzos
  • amnesia
17
Q

Propofol

  • mechanism
  • class
  • function in anesthesia
A
  • alteration of membrane fluidity
  • on its own
  • induction
18
Q

Ketamine

  • mechanism
  • class
  • function in anesthesia
A
  • NMDA (?) unknown
  • on its own
  • anesthetic, analgesic, sedative
  • *drawback is emergence reactions**