ANTIBIOTICS

Question 1

Mild community acquired pneumonia.

Answer 1

Amoxicillin.

If penicillin allergy: doxycycline.

Question 2

Severe community acquired pneumonia.

Answer 2

Co-amoxiclav IV + Doxycycline/Clarithromycin IV.

If penicillin allergy:
Levofloxacin IV

Question 3

Severe hospital acquired pneumonia or aspiration pneumonia.

Answer 3

IV amoxicillin + metronidazole + gentamicin

If penicillin allergy:
IV Co-trimoxazole + metronidazole +/-gentamicin.

Question 4

Non-severe hospital acquired pneumonia or aspiration pneumonia.

Answer 4

PO amoxicillin + metronidazole

If penicillin allergy:
Co-trimoxazole + metronidazole.

Question 5

Acute exacerbation of COPD.

Answer 5

1. amoxicillin.

2. Doxycycline.

Question 6

Sub-acute endocarditis of native valve.

Answer 6

amoxicillin + gentamicin

Question 7

Acute endocarditis of native valve.

Answer 7

Flucloxacillin.

Question 8

Endocarditis of prosthetic valve or suspected MRA

Answer 8

Vancomycin IV + Rifampicin + Gentamicin.

Rifampicin should be added in delayed, on day 3-5.

Question 9

Severe endocarditis of native valve + risk of resistant pathogens.

Answer 9

Vancomycin IV + meropenem IV.

Question 10

Severe C. Diff infection

Answer 10

Vancomycin +/- IV metronidazole

Question 11

Non-severe C. Diff infection.

Answer 11

Metronidazole

Question 12

Peritonitis/biliary tract/intra-abdominal infection.

Answer 12

IV amoxicillin (streptococci and enterococci) + metronidazole (anaerobes) + gentamicin (aerobic coliforms).

If penicillin allergy:
Vancomycin IV + metronidazole + gentamicin.

Question 13

Mild proven spontaneous bacterial peritonitis.

Answer 13

Co-trimoxazole

Question 14

Severe proven spontaneous bacterial peritonitis.

Answer 14

Piperacillin/tazobactam.

Question 15

IV drug user endocarditis.

Answer 15

Flucloxacillin.

Question 16

Staph. aureus endocarditis.

Answer 16

Flucloxacillin.

Question 17

Viridans streptococci endocarditis.

Answer 17

Benzylpenicillin IV + Gentamicin IV

Question 18

Enterococcus sp. endocarditis.

Answer 18

Amoxcillin + Gentamicin IV
If penicillin allergy:
Vancomycin + Gentamicin IV.

Question 19

Staph. epidermidis endocarditis.

Answer 19

Vancomycin + Gentamicin IV + rifampicin PO

Question 20

abscess due to coliforms.

Answer 20

Gentamicin.

Question 21

Abscess due to anaerobes.

Answer 21

Metronidazole.

Question 22

Abscess due to enterococcus sp.

Answer 22

Amoxicillin.

Question 23

Intra-abdominal sepsis.

Answer 23

Gentamicin + amoxicillin + metronidazole.

If penicillin allergy:
Co-trimoxamole + gentamicin + metronidazole.

Question 24

For prophylaxis of GI/hepatobiliary surgery.

Answer 24

Gentamicin + metronidazole.

Question 25

Staph. aureus pneumonia.

Answer 25

Flucloxacillin or vancomycin if MRSA.

Question 26

Klebsiella pneumonia.

Answer 26

Cefotaxime

Question 27

Pseudomonas pneumonia

Answer 27

Ceftazidime/ciprofloxacin + aminoglycide

Question 28

Mycoplasma pneumonia

Answer 28

Clarithromycin/ciprofloxacin

Question 29

Legionella pneumonia

Answer 29

levofloxacin/moxifloxacin/rifampicin

Question 30

Chlamydophila pneumonia
or
Chlamydiophilia psittaci

Answer 30

Doxycycline/clarithromycin

Question 31

Pneumocystis jiroveci pneumonia

Answer 31

Co-trimoxazole

Question 32

Fungal pneumonia

Answer 32

amphotericin

Question 33

Pneumococcal pneumonia

Answer 33

amoxicillin/benzylpenicillin/cephalosporin

Question 34

Staphylococcal pneumonia

Answer 34

Flucloxacillin

if MRSA suspected, then add Vancomycin.

Question 35

Viral pneumonia

Answer 35

Ciprofloxacin and co-amoxiclav.