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Flashcards in Antiinfective Drug Facts Deck (155)
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1
Q

Age limit for fluoroquinolones

A

18

2
Q

BBW’s for fluorquionolones

A
  • May cause tendon rupture-especially the Achilles tendon

- Avoid giving to pt’s with myasthenia gravis

3
Q

Myasnethia gravis

A

automimmune neuromuscular disease-causes muscle weakness

4
Q

What other concern is associated with Fluoroquinolones?

A

lowers the seizure threshold

5
Q

What shoudl pt’s avoid while taking fluoroquinolones?

A

multivitamins/dairy of calcium supplement

causes chelation

6
Q

tablet trade name for moxifloxacin

A

Avelox

7
Q

ophthalmic solution trade name for moxifloxacin

A

Vigamox

8
Q

Indication for Vigamox

A

bacterial conjunctivitis

9
Q

generic for Avelox

A

moxifloxacin

10
Q

generic for Vigamox

A

moxifloxacin

11
Q

Indication for levofloxacin Op. solution

A

bacterial conjunctivitis

12
Q

tablet trade name levofloxacin

A

Levaquin

13
Q

generic of Levaquin

A

levofloxacin

14
Q

what fluoroquinoloone has the highest incidense

A

Levaquin (levofloxacin)

15
Q

trade name of besifloxacin

A

Besivance

16
Q

generic for besivance

A

besifloxacin

17
Q

dosage form of Besivance

A

Op. Suspension

18
Q

dosage form of besifloxacin

A

Op. suspension

19
Q

Indication for Besivance

A

bacterial conjunctivitis

20
Q

indication for besifloxacin

A

bacterial conjunctivitis

21
Q

Trade name for ophthalmic ofloxacin

A

Ocuflox

22
Q

generic for Ocuflox

A

ofloxacin

23
Q

Dosage form for Oculfox

A

Op. solution

24
Q

other dosage form of ofloxacin

A

otic solutioin

25
Q

Indication for Ocuflox

A

bacterial conjunctivitis

26
Q

generic for Zymaxid

A

gatifloxacin

27
Q

trade name for gatifloxacin

A

Zymaxid

28
Q

indication for Zymaxid

A

bacterial conjunctivitis

29
Q

indication for gatifloxacin

A

bacterial conjunctivitis

30
Q

dosage form for gatifloxacin

A

Op. solution

31
Q

dosage form for Zymaxid

A

Op. solution

32
Q

trade tablet name for ciprofloxacin

A

Cipro

33
Q

trade name for Op. soln and ointment for ciprofloxacin

A

Ciloxan

34
Q

Inidcation for Ciloxan

A

bacterial conjunctivitis

35
Q

auxillary label for Ciprodex

A

Shake well

36
Q

ingredients in Ciprodex

A

ciprofloxacin, dexamethasone

37
Q

indication for Ciprodex

A

bacterial conjunctivitis

38
Q

Ingredients in Tobradex

A

tobramycin, dexamethasone

39
Q

what does Tobradex do in children

A

causes glaucoma

40
Q

What is Tobradex not indicated fo

A

bacterial conjunctivitis

41
Q

generic macrolide

A

erythromycin

42
Q

tablet trade name for clarithromycin

A

Biaxin

43
Q

strength(s) for Biaxin tablet

A

250mg, 500mg

44
Q

strength(s) for clarithromycin tablets

A

250mg, 500mg

45
Q

clarithromycin extended release tablet

A

Biaxin XL

46
Q

strength(s) of Biaxin XL

A

500mg

47
Q

strength(s) of clarithromycin extended release

A

500mg

48
Q

strengths for Biaxin granules for oral suspension

A

125/5 250/5

49
Q

How do you store Biaxin suspension?

A

store at room temperature when mixed

50
Q

trade name for azithromycin

A

Zithromax

51
Q

strength(s) for azithromycin tablet

A

250mg, 500mg

52
Q

strengths for azithromycin powder for oral suspension

A

100mg/5ml

200mg/5ml

53
Q

Who reconstitutes azithromycin powder for oral suspension

A

reconstituted in the pharmacy

54
Q

strength of single dose azithromycin powder packet

A

1 gram

55
Q

Instructions for pt’s with 1g Azithromycin powder pack

A

mix with 60ml and drink all at once

56
Q

INdication for 1g powder pack Azithromycin

A

chlamydia

57
Q

dosage form for Z-Max

A

extended-release microspheres for oral suspension

58
Q

Strength for Z-Max

A

2g single dose bottle

59
Q

Who reconstitutes Z-MAx?

A

In the pharmacy with 60ml of H20

60
Q

INstructions for Z-Max to pt’s

A

Drink within 12 hours

Take on empty stomach

61
Q

trade name for op. solution of azithromycin

A

AzaSite

62
Q

polymer found in AzaSite

A

DuraSite

63
Q

Indication for AzaSite

A

bacterial conjunctivitis

64
Q

Dosing interval for AzaSite

A

1 drop twice daily for 2 days, then 1 drop daily for the next 5 days

65
Q

Storage instructions for AzaSite

A

store in fridge at pharmacy-pt can store at room temperature

66
Q

Allergy considerations for Cephalosporins

A

ceph’s are related to penicillins-pt’s allergic to pennicillins may be allergic to ceph’s

67
Q

Rule about ceph’s generations

A

the higher the generations go, the more gram- activity and less gram+ activity

68
Q

Gen. of Keflex

A

1st Gen

69
Q

Gen. of cephalexin

A

1st Gen

70
Q

dosage forms of Keflex

A

capsule

powder for oral suspensions - fridge after reconstitution

71
Q

trade name for cefadroxil

A

none

72
Q

Gen. of cefadroxil

A

1st Gen

73
Q

dosage forms for cefadroxil

A

capsule

powder for oral suspension - fridge after reconstitution

74
Q

trade name for cefuroxime

A

Cefdin

75
Q

Gen. of Cefdin

A

2nd Gen

76
Q

generic name for Cefdin

A

cefuroxime

77
Q

Gen. of cefuroxime

A

2nd Gen

78
Q

Dosage forms of Cefdin

A

tablet

powder for oral suspension - fridge after reconstitution

79
Q

trade name for cefixime

A

Suprax

80
Q

generic name for Suprax

A

cefixime

81
Q

Gen. of Suprax

A

3rd Gen

82
Q

gen for cefixime

A

3rd gen

83
Q

dosage forms for Suprax

A

tablet

powder for oral suspension - store at room temp after reconstitution

84
Q

trade name for cefditoren

A

Spectracef

85
Q

generic name for Spectracef

A

cefditoren

86
Q

dosage form for Spectracef

A

tablet - take with food

87
Q

trade name for cefdinir

A

none

88
Q

gen for cefdinir

A

3rd Gen

89
Q

dosage form for cefdinir

A

caspule

powder for oral suspension - store at room temp

90
Q

Important info about cefdinir

A

can cause red stool in children

91
Q

Generic name for Bactroban

A

mupirocin

92
Q

trade name for mupirocin

A

Bactroban

93
Q

Indication for Bactroban

A

impetigo-blisters around the mouth

94
Q

strength of mupirocin

A

2%

95
Q

strength for Bactroban

A

2%

96
Q

mupirocin trade name for intranasal ointment

A

Bactroban Nasal

97
Q

Indication for Bactroban Nasal

A

eradicate MRSA-methicillin resistant staph aureus

98
Q

trade name for retapamulin

A

Altabax

99
Q

generic name for Altabax

A

retapamulin

100
Q

strength of Altabax

A

1%

101
Q

strength of retapamulin

A

1%

102
Q

dosage form of Altabax

A

ointment

103
Q

dosage form for retapamulin

A

ointment

104
Q

Indication for Altabax

A

impetigo

105
Q

Indication for retapamulin

A

impetigo

106
Q

tablet size for Lamisil

A

250mg

107
Q

tablet strength for terbinafine

A

250mg

108
Q

onychomychosis

A

fungal infection of the toe or finger nail

109
Q

tinea unguium

A

fungal infection of the toe or finger nail

110
Q

trade name for terbinafine cream

A

Lamisil AT

111
Q

strength of Lamisil AT cream

A

1%

112
Q

strength of terbinafine cream

A

1%

113
Q

Indication(s) for Lamisil

A

onychomycosis

114
Q

Indication(s) for Lamisil AT

A

tinea corporis
tinea pedis
tinea cruris

115
Q

What is tinea corporis?

A

Ring worm

116
Q

What is tinea pedis?

A

athlete’s foot

117
Q

what is tinea cruris?

A

Jock itch

118
Q

What SALAD drug is often confused with Lamisil?

A

Lamictal(lamotrigine)

119
Q

dosage forms of fluconazole

A

tablet

powder for oral suspension

120
Q

dosage forms of Diflucan

A

tablet

powder for oral suspension

121
Q

Storage for Diflucan suspension

A

store at room temp

122
Q

storage for fluconazole suspension

A

store at room temp

123
Q

Indications for Diflucan

A

oral candidiasis
esophageal candidiasis
vaginal candidiasis

124
Q

Yeast that causes candidiasis

A

candida albicans

125
Q

Dose of DIflucan for vaginal candidiasis

A

150mg single oral dose

126
Q

dosage forms of Zovirax

A
capsule
tablet
ready-to-use oral suspension
cream
ointment
127
Q

indications for Zovirax capsule

A

herpes genitalis
herpes zoster
vericella zoster
herpes labialis

128
Q

Indications for Zovirax tablet

A

herpes genitalis
herpes zoster
vericella zoster
herpes labialis

129
Q

Indications for Zovirax ready-to-use suspension

A

herpes genitalis
herpes zoster
vericella zoster
herpes labialis

130
Q

What antiviral is a prodrug?

A

Valtrex (valacyclovir)

131
Q

What does Valtrex convert into?

A

acyclovir

132
Q

Indication for Zovirax cream

A

herpes labialis

133
Q

Indication for Zovirax ointment

A

genital herpes

134
Q

Indication for acyclovir cream

A

herpes labialis

135
Q

Indication for acyclovir ointment

A

genital herpes

136
Q

What is herpes genitalis?

A

genital herpes

137
Q

What is herpes zoster?

A

Shingles

138
Q

What is varicella zoster?

A

Chickenpox

139
Q

What is herpes labialis?

A

Cold sore

140
Q

Available strengths for Valtrex

A

500mg, 1000mg

141
Q

Available strengths for valacyclovir

A

500mg, 1000mg

142
Q

Dosing interval for Valtrex treating initial herpes genitalis

A

1g twice daily for 10 days

143
Q

Dosing interval for Valtrex treating recurrent herpes genitalis

A

500mg twice daily for 3 days

144
Q

Dosing interval for Valtrex treating herpes zoster

A

1g three times daily for 1 week

145
Q

Dosing interval for Valtrex treating herpes labialis

A

2g in the morning, then 2g in the evening. This is a 1 day dose

146
Q

Dosing interval for Valtrex treating varicella zoster

A

Depends on weight - Three times daily for 5 days

147
Q

What does a neuroaminidase do?

A

Inhibits the key protein needed for viral replication

148
Q

Dosage forms for Tamiflu

A

capsule

powder for oral suspension

149
Q

Storage info for Tamiflu suspension

A

store in fridge after reconstitution

150
Q

INstructions for patients taking Tamiflu

A

take with food - reduces the nausea associated with taking Tamiflu

151
Q

Dosing interval for Tamiflu for treatment

A

Twice daily for 5 days

152
Q

Dosing interval for Tamiflu for prophylaxis

A

1 dose daily for 10 days

153
Q

Dosage forms for Differin

A

cream
gel
lotion

154
Q

What causes red stool in children

A

Cefdinir

154
Q

Definition of comedo

A

Initial lesion of acne
Differin reduces comedo formation
Takes 2 to 3 months for a noticable difference