Application of stem cells Flashcards Preview

(2020-21 BY2BT2) Biotechnology > Application of stem cells > Flashcards

Flashcards in Application of stem cells Deck (13)
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1
Q

What is the most well-established and widely used stem cell treatment?

A

The transplantation of blood stem cells to treat diseases.

2
Q

How many patients are treated with blood stem cells in Europe each year?

A

More than 26,000 patients

3
Q

What stem cells been used for patients with severe burns on very large areas of the body?

A

Since the 1970s, skin stem cells have been used to grow skin grafts for patients with severe burns on very large areas of the body.

4
Q

TRUE or FALSE:

Currently, these are very few stem cell therapies that have been thoroughly established as safe and effective treatments.

A

TRUE

5
Q

What was the first stem cell-based medicinal product approved in the Western world?

A

Holoclar®

Uses a particular type of eye stem cell, called a limbal stem cell, to repair the cornea after injury; restoring sight.

6
Q

Blood stem cells: the pioneers of stem cell research

A
7
Q

What are the main sources of stem cells?

A
  • Bone Marrow
  • Blood stream
  • Umbilical cord
8
Q

Future applications of stem cells

A
9
Q

Patient derived
Induced pluripotent stem cells

A
10
Q

What are the potential uses of stem cells?

A
  • Improve our understanding of how the body develops from a fertilized egg; this can also provide insights into how our adult tissues are maintained and repaired in health
  • Understand how diseases occur and develop; a number of diseases, such as cancer or birth defects, are the result of problems in the process of differentiation from stem cells to more specialized cells
  • Search for and test potential new drugs by studying cells in the laboratory
11
Q

Drug development

A
12
Q

Drug screening/development

A
13
Q

The embryonic stem cell test

A

•Only validated in vitro assay for potential embryotoxicants