Arboviruses Flashcards

0
Q
Which is not a Bunyavirus?
A.Rift Valley fever
B.Crimean Congo hemorrhagic fever
C.Sandfly fever
D.Dengue hemorrhagic fever
A

D

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1
Q
Humans may be \_\_ hosts of Arboviruses.
A.intermediate
B.definitive
C.accidental
D.A & B
E.B & C
A

E

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2
Q
Which is not a member of Flaviviridae?
A.Japanese encephalitis 
B.Yellow fever
C.Chikungunya
D.Dengue hemorrhagic fever
A

C

Chikungunya is a member of Togaviridae

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3
Q
Which is not common in our country?
A.Japanese encephalitis 
B.Yellow fever
C.Chikungunya
D.Dengue hemorrhagic fever
A

b

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4
Q

A)Family Flaviviridae
B)Enveloped
C)(+)ssDNA virus
D)fifth genotype still under observation

False abt dengue virus

A

C

(+)ssRNA dapat

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5
Q

False about Aedes mosquito
A)Infected male mosquito transmits dengue
B)Found in tropical and subtropical areas
C)Breed in clean, stagnant water
D)none of the 3

A

A

Female dapat

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6
Q

False about Aeses
A.Primarily a nocturnal feeder
B.Live around human habitation, generally “indoor”
C.Lay eggs and produces larvae preferentially in artificial containers

A

A

Daytime dapat

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7
Q

Aedes species that is Usually found outdoors (in stagnant waters collected on banana trees)

A

Aedes albopictus

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8
Q

Which is false?
A)Attachment to specific receptors on many different cell types from many different species
B)When coated with antibodies, Ig can attach to Fc receptors on surface of macrophages and monocytes
C)Both are false
D)Both are true

A

B

Antigens, not antibodies

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9
Q
\_\_ binds to the virus (second infection) and forms the “infectious complex” 
A. IgE
B. IgG
C. IgM
D. IgA
A

B

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10
Q
“infectious complex” binds to \_\_receptor on surface of macrophages & monocytes
A)Fa
B)Fab
C)Fbc
D)Fc
A

D

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11
Q
Virus is taken up by \_\_
A.exocytosis
B.pinocytosis
C.endocytosis
D.transcytosis
A

C

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12
Q

Sequence

A)Recognition of viral antigens on the surface of infected
B)T-cell proliferation
C)Induction of memory T-cell
D)T-cell lyses the virus

A

C B A D

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13
Q

Mesenchymal Cells →Plasma leakage→ SHOCK→ Hemostatic system→ Hemorrhage

What is wrong with the pathogenesis of dengue?

A

Endothelial, not mesenchymal

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14
Q

Classical dengue vs dengue hemorrhagic fever: main difference

A

Classic dengue- severe myalgia

Dengue hemorrhagic fever- bleeding

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15
Q
Hematemesis is \_\_
A.vomiting of blood
B.passage of black and tarry stools
C.passage of fresh blood through anus with or in stools
D.none of the above
A

A

16
Q
Melena is
A.vomiting of blood
B.passage of black and tarry stools
C.passage of fresh blood through anus with or in stools
D.none of the above
A

B

17
Q
Hematochezia is
A.vomiting of blood
B.passage of black and tarry stools
C.passage of fresh blood through anus with or in stools
D.none of the above
A

C

18
Q
All are definitive symptoms of DHF except
A.melena
B.hematemesis
C.hematochezia
D.myalgia
A

D

19
Q

Enumerate theories on DHF Pathogenesis

A

Antibody enhancement theory

Viral virulence theory

20
Q

Antibody enhancement theory is AKA __

A

Halstead’s Theory

21
Q

Viral virulence theory is AKA __

A

Rosen’s Theory

22
Q

False about Halstead’s Theoy

  1. secondary dengue is not a risk factor
  2. heterotypic antibodies from a previous infection promote increased viral replication within mononuclear leukocytes
  3. immunologic processes occur
  4. dengue virus-infected cells are eliminated
A

1

23
Q

Treatment for dengue

A

Fluid replacement

24
Q

Enumerate lab diagnostic methods for dengue

A

Identifcation via serotyping
Isolation
Serology

25
Q

Elimination of adult mosquitoes is always effective

T or F?

A

F

26
Q

It is believed that Manila is the reason of the respreading of dengue in the Americas in 2002 through __

A

tires in ships

27
Q

family of Chikungunya

A

Togaviridae

28
Q
false about Chikungunya
A. enveloped
B. (-)ssRNA virus
C. limited to Asia-Pacific region
D. vaccine is not available
A

B

(+) dapat

29
Q

enumerate vectors of Chikungunya

A

Aedes aegypti

Aedes albopictus

30
Q

main presentation of Chikungunya

A

joint pains

31
Q

family of Japanese Encephalitis

A

Flaviviridae

32
Q
false about Japanese Encephalitis
A. naked
B. (+)ssRNA virus
C. mostly neurologic symptoms
D. vaccine is available
A

A

enveloped dapat

33
Q

vector of Japanese Encephalitis

A

Culex tritaeniorhyncus

34
Q

false about Culex tritaeniorhyncus
A. breeds in rice fields
B. infects in peridomestic areas
C. humans are only natural host

A

C