B4. Radiotherapy, surgical, and pharmacological treatment of esophagus tumours  Flashcards Preview

Oncology > B4. Radiotherapy, surgical, and pharmacological treatment of esophagus tumours  > Flashcards

Flashcards in B4. Radiotherapy, surgical, and pharmacological treatment of esophagus tumours  Deck (11):
1

How are tumors of upper segment of esophagus treated? Lower 2/3rds of esophagus?

Chemoradiotherapy for top 1/3rd. Lower 2/3rd is treated with surgical resection

2

How are T3 N0-3 M0 and T2 N1-3 M0 are treated with what before surgery?

Neoadjuvant chemoradiotherapy

3

What happens if esophageal cancer has metasized

Palliative chemotherapy and/or radiotherapy

4

How are early T1 surgeries treated

Endoscopic mucosectomy or endoscopic submucosal dissection

5

3 basic types of resection

-Two incisional Ivor-Lewis procedure
-Tri-incisional McKeown procedure
-Pinotti esophagectomy

6

What kind of radiotherapy is given for esophageal tumors?

External beam radiotherapy and internal radiation

7

Preoperative treatment

External beam therapy (total dose of 41.4-50.4 greys) with FOLFOX protocol and oxaliplatin + 5-Fluorouracil.
Or
CROSS protocol + taxane + carboplating

8

What is folfox protocol

FOL– Folinic acid (leucovorin)
F – Fluorouracil (5-FU)
OX – Oxaliplatin (Eloxatin)

9

What is the palliative treatment for esophageal tumors

Brachytherapy

10

Side effects of radiotherapy with the esophagus

-Inflammation ,pain, and temporary swallowing difficulties.
-Accompanied vomiting/nausea
-Most severe side effect of radiotherapy is esophageal fistula perforation

11

Metastatic esophageal tumor chemo treatment

Platinum and 5-FU
Ramucirumab or pembrolizumab