BioChem Flashcards

1
Q

Which is not a regulatory enzyme of krebs?

A

succinate dehydrogenase (b/c it’s also in ETC)

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2
Q

In conversion of Pyruvate → acetyl CoA via pyruvate dehydrogenase complex, classified as _______ reaction?

A

decarboxylation

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3
Q

Starving, what state are you in?

A

Gluconeogenisis (making carb from non carb)

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4
Q

Which A.A. = aromatic

A

Tryptophan

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5
Q

Which A.A. aids in transportation of fatty acids into mitochondria?

A

methionine (b/c carnirine= lysine & methionine)

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6
Q

What reaction is niacin involved in?

A

Oxidation/reduction

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7
Q

B Vitamin in remetylization of homocysteine

A

B12 (or B9)

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8
Q

What vitamin aids in conversion of ketoacid → amino acid

A

B6 (trans. amination)

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9
Q

Insulin Binding →

A

chromium

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10
Q

What binds to iron & is storage form of iron?

A

Feritin

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11
Q

Good Vit. C=

A

Fruits / Veggies

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12
Q

What fatty acid can body synthesize?

A

palmitic acid

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13
Q

What helps absorb iron?

A

Vitamin C

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14
Q

Glucose + ______ = Lactose

A

Galactose

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15
Q

Which disacharide contains A1-6 linkage

A

isomaltose

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16
Q

Lipoprotein VLDL responsible for transport of _______ ?

VLDL = never dietary
LDL = Leave the liver = Bad
HDL = carries cholesterol
A

Endogenous triglycerides

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17
Q

LDL is responsible for?

A

Endogenous Cholesterol

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18
Q

What doesn’t contribute to cholesterol in obese

A

no answer written down..????

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19
Q

Which is the DNA complimentary strand for:

A

3’ TACGATGC 5’ (at the golf course)

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20
Q

rate limiting enzyme for glycolysis =

A

PPK

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21
Q

comitted step in glycolysis =

A

no answer written down..????

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22
Q

What step in krebs doesn’t produce NADH?

A

Succinate → Fumarate

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23
Q

Where does glycolysis occur?

A

Cytosol

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24
Q

Alpha keto form of which A.A. = intermediate in krebs?

A

Glutamate

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25
Q

What/s formed in succinate → fumerate

A

FADH 2

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26
Q

What contains sulfur & has antibacterial, viral, fungal properties?

A

Garlic

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27
Q

What isn’t an example of anaplerotic reaction?

anaplerotic means filling up

A

Glucose → G6P (Glycolysis)

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28
Q

Following is example of a _______ reaction =

2RCo2H→ (RCO)20+H2O

A

Dehydration

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29
Q

Cereals are low in

A

Lysine

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30
Q

Which complex of electron transport system contains copper?

A

Cytochrome C Oxidase

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31
Q

Which enzyme controlled through product ‘inhibitory’ allows skeletal muscles cells to accumulate glucose ?

inhibitory = rate limiting

A

PPK (phosphofruscto kinase)

32
Q

Which of these actions occur during a lanine cycle?

A

Pyruvate is converted to glucose in the liver

33
Q

The malic enzyme catalyzes conversion of malate to pyruvate and provides [which substance used in F.A biosynthesis]?

A

acetyl CoA

34
Q

Richest source of Vit. E =

A

Oil (vegetable oil)

35
Q

Hydrolysis of amylopectin by amylase →

A

Amylose

36
Q

Which hormone enhances activity of glycogen phosphorylase in skeletal muscle?

A

epinepurine (or Glucagon)

37
Q

Glucose precursors derived from _____?

A

Amino Acids

38
Q

Principle carb produced by action of alpha-amylase on dietary starch

A

maltose

39
Q

A.A. derived from proteins are catabolized to products which directly enter the ______ for further oxidation to Co2

A

tricarboxylic acid cycle (TCA)

40
Q

Enzymes that catylize breakdown of maltose from ______?

A

Small intestine

41
Q

Which type of F.A is in olive oil?

A

monounsaturated

42
Q

A lack of lipoprotein lipase results in ______?

A

elevated chylomicron following fatty meal

43
Q

Phosphate groups of ATP are linked by _____ bonds?

A

Phosphoanhydride

44
Q

Triacylglycerols transported from intestinal cells to adipose cells within ______?

A

Chylomicron

45
Q

What hormone ↑ many metabolic processes by ↑

A

Epinephrine (or Glucagon)

46
Q

Dietary supplementation of therapeutic folic acid maybe be detrimental because..

A

Can mask B12 deficiency

47
Q

What compound is simple sugar?

A

dihydroxyacetone

48
Q

What vitamin made by intestinal flora?

A

Vitamin K

49
Q

What compound catylizes formation of GTP in TCA?

A

Succinate thiokinase

50
Q

What is characteristic of myoglobulin?

A

It’s a single polypeptide

51
Q

Toxicity of many pesticides result from ________ enzyme inhibition?

A

irreversible

52
Q

Which of these is C-4 epimere of Glucose?

A

Galactose

[*manose is C-2 epimere to Glucose]

53
Q

Oxidation of what = ketone bodies?

A

Fatty Acids

54
Q

Good source of Omega 3 =

A

Salmon

55
Q

Vitamin K = essential to the synthesis of these substances?

A

Prothrombin

56
Q

Dietary lipids converted to ______ by pancreatic lipase

A

Lipoprotein

57
Q

Which mineral is required for activity of most glycolytic enzymes?

A

Sulfur (B vitamin [thiamine, biotin])

58
Q

Glucagon activates which enzyme in plasma membrane of hepatocytes?

A

Adenyl cyclase

59
Q

Bonding between F.A. & glycerol in a Z-monacyl-Glycerol is best described as what?

A

Ester linkage

60
Q

When equilibrium is Pos. = 1 then free energy charge is (-)

A

-1.36

61
Q

In TCA, isocitrate dehydrogenase converts to?

A

Alphaketoglutanate

62
Q

Which amino acid initiates protein synthesis in humans?

A

methionine

63
Q

What hormone affects anabolism / catabolism phase of protein metabolism?

A

Glucocorticoids (cortisol)

64
Q

Disacharide B1→ 4

A

Lactose

65
Q

Saturation levels of substrate concentration in an enzyme - catylized reaction cause progress..

A

Neg. cooperativity

66
Q

Tryptophan →

A

Niacin

67
Q

Coenzyme for oxidative decarboxylation processes

A

thiamine pyrophosphate (B1) (decarboxylation)

68
Q

Protein complementary allows vegan diet to supply sufficient amounts of ______?

A

Essential A.A.

69
Q

Enzyme that catylizes peptide bond formation during protein synth. @ ribosome

A

Peptidyl transferase

70
Q

1 carbon transfers during production of purine & pyrimidines are directly dependent upon?

A

Pyridoxine

71
Q

Primary function of Vitamin D is to regular absorption and metabolism of which mineral?

A

Calcium & Phosphorus

72
Q

Cholesterol is not a precursor of what?

A

Lecithin

73
Q

Which of these characterizes gout?

A

Purine overproduction

74
Q

Which is a spontaneous reaction?

A

Gibb’s free energy is negative

75
Q

Bile acids contain carboxyl group in side chain that is bound in amide linkage with _____?

A

Taurine (constituent of bile)

76
Q

Arginase catalyzes conversion of arginine into _____ and urea?

A

Ornother (ArCo)