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Flashcards in Blood Products Deck (12)
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1

Packed Red Blood Cells (PRBCs) Components:

RBCs

2

Whole Blood Components:

RBC
WBC
Plasma
Platelet debris
Fibrinogen

3

Fresh Frozen Plasma Components:

All coagulation factors
Fibrinogen
Plasma proteins

4

Platelets Components:

Platelets

5

Cryoprecipitate Components:

Fibrinogen
Factor 8
Factor 13
von Willinbrand's Factor

6

PRBC Indications:

RBC replacement (increase CaO2)

7

Whole Blood Indications

RBC replacement/blood volume replacement (rarely used in OR)

8

FFP Indications:

Coagulopathy (PT or PTT > 1.5x control)
Warfarin reversal (acute need)
Antithrombin 3 deficiency
Massive transfusion
DIC
C1 esterase deficiency (heredity angioedema)

9

Platelets Indications:

Thrombocytopenia (<50,000 - invasive procedures, neuraxial blocks, most surgeries)
Thrombocytopenia (<100,000 - eye and neurosurgery)
Qualitative platelet defect
(*highest risk of bacterial contamination*)

10

Cryoprecipitate Indications:

Fibrinogen deficiency (<80-100)
vWB disease
Hemophilia

11

FFP doses:

Warfarin reversal: 5-8 mL/kg
Coagulopathy: 10-20 mL/kg (increases factor concentration by 20-30%)

12

Cryoprecipitate dose:

5 bag pool increases Fibrinogen by 50 mg/dL