age range of kawasaki disease
<4
what is kawasaki
pediatric vasculitis that damages, aneurysm or thrombus -> MI
cause of kawasaki
idiopathic
symptoms of kawasaki
persistent fever, cervical lympphadenopathy, strawberry tongue
what type of hypersensitivity is wegener granulomatosis
2
wegener granulomatosis involves which areas mainly
kidneys and upper/lower resp tracts
what happens in wegener granulomatosis
necrotizing vasculitis ->ischemia
wegener granulomatosis untreated
80% lethal, usually mid age males
what is thromboangiitis obliterans
medium size arteries have inflam and thrombosis -> vascular insufficiency
where is thromboangiitis obliterans typically
feet and hands
thromboangiitis obliterans how to know if ischemia
painful extremities, cyanosis/cold
thromboangiitis obliterans passively get
ulcerations and gangrene
what increases likelihood of thromboangiitis obliterans
smoking
what is exaggerated vasoconstriction causing pallor and cyanosis
raynauds phenomenon
if you have chronic raynauds what happens
atrophy of skin, ct, and muscles
who gets raynauds
young adult females
what is raynauds secondary to
atheroslerosis, buergers disease, sle, scleroderma, and atherosclerosis
90% of venous diseases (3)
- varicose
- phlebothrombosis: venous thromb w/o inflam
- thrombophlebitis: venous thromb following inflam
MC area of varicose and look
tortuous and dilated, mc legs
how often does varicose happen
1/3 of females
risk varicose and symptoms
obesity, pain and edema
thrombophlebitis
thrombosis w/ inflam
t or f thrombophlebitis typically have dvt
t
localized thrombophlebitis symptoms
cyanosis/erythema, edema, pain
what is the red white and blue disease
raynauds
risks of thrombophlebitis
surgery, prego, obesity, IMMOBILIZATION, chf
what could thrombophlebitis cause
pulmonary embolism
2 types of lymphedema
- congenital : abnormalities
2. obstruction to normal lymph vessel
lymphangitis
acutre lymphatic vessel inflam: bacteria
t or f most vascular tumors are malig
f benign, but can be aggressive (kaposi sarcoma)
rare: highly aggressive angiosarcoma
where do vascular tumor orig
endothelial cells
what has increased growth in hemangioma
capillary
where is hemangioma usually
face, head, neck
fx hemangiomas
75-90% resolve by 7
what has red painful streaks along lymph channel
lymphangitis
cause of kaposi sarcoma
hhv 8
what is HHV 8 a defining disease for?
aids
who gets angiosarcoma
older adults
is angiosarcoma systemic?
usually local invasive
where do angiosarcoma usually metas?
lymph nodes
angiosarcoma never recur
f, poor prognosis
MC locations angiosarcoma
skin, breast, liver
what causes hepatic angiosarcomas
foreign bodies….irradiation
best vascular intervention
stent: luminal patency and antithrombotic meds for chronic
what replace or bypass arteries?
vascular grafts
prob w/ synthetic grafts
prone to thrombosis
which vein used as vascular replacement
great saphenous: 50% @ 10 yrs