Breast 3 Flashcards Preview

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Flashcards in Breast 3 Deck (14)
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0
Q

Which breast cancer patients get chemotherapy?

A

All patients with node positive disease and all premenopausal women

1
Q

Management –

stage 0 and stage 1 breast cancer with tumor <1 cm?

Stage 1 cancer with 1-2 cm tumor?

For stage 2 cancer?

A

Lumpectomy, axillary sampling, radiation therapy (if ER positive, add hormone therapy)

Lumpectomy, axillary sampling, radiation therapy, and adjuvant therapy (hormonal or chemo)

Modified radical mastectomy, axillary sampling, radiation therapy, Agilent therapy

2
Q

Follow-up for postoperative breast cancer patients?

A

Two visits a year with CXR and LFTs

If had lumpectomy, mammogram every six months for 2 years

3
Q

Management for stage III cancer? Stage IV cancer?

A

Neoadjuvant chemotherapy before surgery

Palliative radiation and chemotherapy. Surgery only for local control of primary tumor

4
Q

Histopathology of the suspected breast tumor shows cancer cells invading dermal lymphatics and vessels – diagnosis?

A

Inflammatory carcinoma

5
Q

Five years post breast cancer surgery, patient presents with elevated LFTs – suspect? Tests?

A

Suspect metastasis to the liver. Contrast enhanced CT scan of the abdomen

if poor renal function MRI with gadolinium enhancement

6
Q

Five years post breast cancer surgery, Patient presents with a femur fracture – suspect? Next steps?

A

Pathologic fracture secondary to metastasis

Orthopedic repair, Local cancer control with irradiation

7
Q

Five years post breast cancer surgery patient develops decreased sensation and motor function in the right leg – Suspect? Management?

A

Extradural metastasis to the spine. MRI, steroids, cord decompression and radiation

8
Q

Five years post breast cancer surgery presents with new onset seizures and focal findings – suspect? Management?

A

Metastasis to the brain – CT/MRI followed by steroids and surgery/irradiation

9
Q

Five years post breast cancer surgery, presents to emergency department with coma/confusion and no focal findings – suspect?

A

Acute hypercalcemia due to bony metastasis or parathyroid related peptide

10
Q

Breast-feeding mother develops painful breast, low-grade fever, and red, tender, indurated breast mass and shotty nodes – differential and treatment?

A
  1. Mastitis – warm compress, antibiotics

2. Abscess – open surgical drainage

11
Q

Breast-feeding mother develops painful breast, low-grade fever, and red, tender, indurated breast mass and shotty nodes – Does not respond to multiple different antibiotics – suspect?

A

Inflammatory carcinoma – get biopsy

12
Q

Changes in treating breast cancer in pregnancy?

A
  1. Postpone radiation until after delivery (so discourage lumpectomy in early pregnancy because of the need for radiation)
  2. Chemotherapy after the first trimester
13
Q

Treatment for male with breast cancer?

A

Mastectomy and postoperative radiotherapy