[C] 1.39 Gangrene Flashcards Preview

Pathology A - General Pathology > [C] 1.39 Gangrene > Flashcards

Flashcards in [C] 1.39 Gangrene Deck (8)
Loading flashcards...
1
Q

Summarise gangrene

A

Secondary phenomenon after necrosis

  • Gangraena sicca
  • Gangraena humida
  • Gas-gangrene
2
Q

Gangraena sicca

A

No bacteria

  • Physiologic (Umbilical cord)
  • Desiccation following necrosis
    • Macroscopic changes:
      • Shrunken
      • Dark brown
      • Hard as wood
      • Histopathology: Recognisable tissue structure
    • Skin
      • Chronic erysipelas
    • Foetus:
      • Mummification
3
Q

Gangrena humida

A

Necrotised area superinfected with saprophytic bacteria (proteolysis)

  • Bacterial infection
  • Appearance
    • Pulpy & soft
    • Grey-black (H2S + Hb
    • Putrid smell
    • Gases
4
Q

Gas-gangrene

A
  • Clostridia
  • Muscles
  • Gas-oedema
5
Q

Gangrena humida: Occurance

A
  • Oral cavity
  • Lungs
  • Uterus
6
Q

Gangrena humida: Specific diseases

A
  • Blackleg-disease
  • Malignant oedema (skin & muscles)
7
Q

Gangrena emphysematosia

A
  • Blackleg disease
  • Malignant oedema
  • Agents (Clostridium)
    • C. chauvoei
    • C. septicum
    • C. histolyticum
  • Produce exotoxin, CO2 & acid
  • Effect of acids & exotoxin:
    • Muscle necrosis
    • Increased vascular wall permeability
8
Q

Gas gangrene

A

General effect of exotoxin

  • Autointoxication
  • Skeletal muscle: Myositis emphysematosa
  • Stomach wall:
    • Swine: Gastritis emphyematosa
    • Lamb: Bradsot
  • Liver: Hepatitis emphysematosa
    • Sheep: Infectious necrotic hepatitis
  • Uterus: Metritis emphysematosa

Decks in Pathology A - General Pathology Class (85):