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Flashcards in C1q stuff Deck (6)
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1
Q

Screening

A

C4 level

cannot rule out if normal

good for between episodes as C1 inhibitor can be normal between episodes

2
Q

C1 q level low in

normal in

A

low in acquired

normal in hereditary

3
Q

C1 inhibitor level can be normal in

A

Type 2 acquired

Type 2 hereditary

4
Q

100% abnormal

A

functional C1 inhibitor assay

5
Q

Types of HAE

A

1- most common, low levels
2- dysfunctional protein, normal or increased levels
4- women, eostrogen related, not due to c cascade, due to factor XII gain of function

6
Q

Types of AAE

A

1- B cell lymphoprolif

2-Ab against C1 inhib (but note 30% HAE also have)