Cardiovascular Pharmacology Flashcards Preview

Fall'20 Pharmacology III COPY > Cardiovascular Pharmacology > Flashcards

Flashcards in Cardiovascular Pharmacology Deck (11)
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1
Q

Adrenergic receptors are divided into two general categories:

A

alpha and beta

2
Q

The two adrenergic receptor types are broken down into additional subtypes. name them:

A

alpha 1 and alpha 2

beta 1 and beta 2

3
Q

these receptors are POSTsynaptic:

A

alpha 1

4
Q

alpha 1 receptors are located in

A

smooth muscle throughout the body

5
Q

the most important CV effect of alpha 1 stimulation is:

A

vasoconstriction

6
Q

stimulation of alpha 1 receptors results in what CV changes?

A

vasoconstriction resulting in:

  • increased PVR
  • Increased LV Afterload
  • increased arterial BP
7
Q

what does stimulation of alpha 1 do to the lungs?

A

bronchoconstriction

8
Q

alpha 2 receptors are located primarily on the:

A

PRE-Synaptic nerve terminals

9
Q

which receptors create a negative feedback loop that inhibits further NE release from the neuron?

A

alpha 2

10
Q

the alpha 2 receptors create a neg fb look that does what?

A

inhibits additional NE release from the neuron

11
Q

stimulation of alpha 2 receptors in the CNS results in:

A

sedation and reduction of sympathetic outflow

-resulting in peripheral vasodilation and lower blood pressure