Cervical cancer Flashcards Preview

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Flashcards in Cervical cancer Deck (16)
1

70% of cervical cancers are caused by which HPV

16 + 18

2

HPV 6 + 11 responsible for ?

genital warts

3

HPV vaccine covers for____-

16, 18, 6, 11

4

most common cancer in women under 35

cervical cancer

5

vaccine is offered to who

girls at age 12-13
catch up available up to 18 years of age

6

how is the vaccine given

series of 2 injections; spaced at least 6 months apart

however if offered older than 15; require 3 injections with the second being given at least a month after the first

7

what is the cervical screening offered

every 3 years between 25 and 49 years

every 5 years between 50 and 64 years

8

what is brachytherapy

uses a radioactive source inserted via an applicator into the vagina/cervix; delivering a higher dose to the tumour with less toxicity to surrounding organs

9

4 cisplatin toxicities

- peripheral neuropathy
- hearing impairment
- bone marrow suppression
- renal impairment

10

risk factors for cervical cancer

- multiple sexual partners
- HPV infection
- early onset of sexual activity
- immunosuppression
- 45 to 59 years

11

symptoms of cervical cancer (although typically late signs )

- abnormal vaginal bleeding
- postcoital bleeding
- mucoid/purulent vaginal discharge

12

management of cervical cancer in pregnancy

MDT
delivery at 35 weeks

13

CIN I

low grade lesion with mildly atypical cellular chamnge in lower 1/3 epithelium

14

CIN II

high grade lesion with moderately atypical cellular changes confined to basal 2/3 epithelium

15

CIN III

severely atypical cellular changes encompassing greater than 2/3 of epithelial thickness and includes full thickness lesions
(severe dysplasia or CIS)

16

CIS

carcinoma in situ