Chapter 14 - Part 1 Flashcards Preview

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Flashcards in Chapter 14 - Part 1 Deck (34)
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1
Q

what percent of the population is affected by Aphthous Ulcers? (Canker Sores)

A

40%

2
Q

what condition is defined as a shallow ulceration on the oral mucosa

A

Aphthous Ulcer (Canker Sore)

3
Q

Canker Sores are painless ulcerations that are >5mm

A

False, they are painful and <5mm

4
Q

Aphthous Ulcers (Canker Sores) are noncontagious and thought to have an autoimmune component

A

true

5
Q

what is the severe version of Aphthous Ulcers in which there is severe ulceration in the mouth including the back of the throat and possibly even genitally called?

A

Behcet Disease

6
Q

Cold Sores are another name for what?

A

Herpes Simplex Virus

Also: Herpetic Stomatitis or fever blisters

7
Q

20% of people with Herpes Simplex Virus are Asymptomatic and the other 80% have acute gingivostomatitis

A

False

80% are Asymptomatic and the remainder have the acute gingivostomatitis

8
Q

Where does the initial infection of Herpes Simplex Virus remain latent?

A

Trigeminal Ganglion (CN V)

9
Q

What is the location of HSV-1 and HSV-2?

A

HSV-1 - Orofacial

HSV-2 - Genital

10
Q

A patient comes to you complaining of a small cluster of blister like lesions on the corner of their mouth. They report some burning and tingling around the area. and mention they had a similar thing happen about a month ago. Upon inspection what do you think this may be?

A

the recurring blisterlooking lesions are vesicles that appear with Herpes Simplex Virus

11
Q

Is there a cure for Herpes Simplex Virus?

A

No

12
Q

Why is Herpes Simplex Virus a serious condition?

A

this is a viral infection which can spread to the brain and possibly cause herpesviral encephalitis

13
Q

If the Herpes simplex virus spreads to the brain which type is it typically? HSV-1 or HSV-2?

A

HSV-1

14
Q

What is the most common oral fungal infection?

A

Oral Candidiasis

15
Q

Is Oral Candidiasis an opportunistic infection

A

Yes

16
Q

A mom brings in their baby and is concerned about a while “membrane” on the baby’s tongue. She had previously thought it looked like milk and went to scrape it off but noticed it was very red underneath and this upset the baby. What is your diagnosis

A

Oral Candidiasis,

- Pseudomembranous Candidiasis (thrush)

17
Q

What is the condition in which there is an overgrowth of capillaries in the gingiva that is sometimes referred to as a “pregnancy tumor”

A

Pyogenic Granuloma

Oral Proliferative Lesion

18
Q

what is a firm, raised, white patch/lesion that cannot be scraped off (is firmly adhered) in the mouth called?

A

leukoplakia

19
Q

Leukoplakia is relatively rare, only 3% of the population gets this, but of those who do have it what percent are pre cancerous?

A

25%

20
Q

What population is Leukoplakia usually seen in?

A

more common in males between 40 and 70

21
Q

what is the term for a pre cancerous, raised white lesion in the mouth?

A

Leukoplakia

22
Q

What is a red velvety area in the mouth that has irregular borders

A

Erythroplakia

23
Q

Erythroplakia is associated with tobacco used

A

True

24
Q

are men or women more likely to have oral cancer?

A

men

25
Q

which is more likely to transition into oral cancer? Leukoplakia or Erythroplakia?

A

Erythroplakia

- 50% of the time

26
Q

What is the mutation associated with oral cancer

A

TP53 Mutation “guardian of the genome”

27
Q

95% of Oral cancers are associated with which cells?

A

Squamous cell carcinomas

28
Q

mouth/throat pain that may cause difficulty swallowing or speaking along with multiple primary tumors is a sign of what?

A

Oral Cancer

29
Q

Oral cancer is most likely to have a single primary tumor develop in the mouth

A

False, MULTIPLE primary tumors are most common

30
Q

usually over 50% of people with oral cancer survive long term

A

False, poor prognosis - LESS THAN 50% long term survival once diagnosed

31
Q

T or F oral cancer that is positive for HPV 16 has a more favorable prognosis than those without this association?

A

True

- this is associated with fewer mutations

32
Q

A patient comes in complaining of mouth pain and upon inspection you discover they have a raised, firm lesion with irregular borders under their tongue. What do you suspect

A

Squamous Cell Carcinoma

33
Q

What is the most common location oral cancer is going to go?

A

Cervical Nodes

34
Q

Squamous Cell Carcinoma most likely metastasizes via lymph system or by hematogenous system?

A

By lymph system

(Carcinoma)