Chemotherapy - induced NV prophylaxis

Question 1

For acute NV prophylaxis

- HIGH non AC =

Answer 1

• HIGH non AC = 5-HT3 + DEX + NK1

For acute NV

Question 2

For acute NV prophylaxis

- HIGH AC =

Answer 2

• HIGH AC = 5-HT3 + DEX + NK1

Question 3

For acute NV prophylaxis

- Carboplatin =

Answer 3

• Carboplatin = 5-HT3 + DEX + NK1

HIGH RISK GRP

Question 4

For acute NV prophylaxis

- Moderate risk =

Answer 4

• Moderate (other than carboplatin) = 5-HT3 + DEX

Question 5

For acute NV prophylaxis

- Low risk =

Answer 5

• Low = 5-HT3 OR DEX OR DOP

Question 6

For acute NV prophylaxis

- minimal risk =

Answer 6

• Minimal = NO PROPHYLAXIS

Question 7

For acute NV prophylaxis

- High risk group include and antiemetic include

Answer 7

(HIGH RISK GRP)

• HIGH non AC = 5-HT3 + DEX + NK1
• HIGH AC = 5-HT3 + DEX + NK1
• Carboplatin = 5-HT3 + DEX + NK1

Question 8

In ___________ prophalaxis

If the NK1receptor antagonist is not available for AC chemotherapy, ____________ is the ______________antagonist

Answer 8

In acute CINV prophalaxis

If the NK1receptor antagonist is not available for AC chemotherapy, PALONOSETRON is the preferred 5-HT3receptor antagonist

Question 9

For DELAYED NV prophylaxis

- High non-AC =

Answer 9

High Non-AC = DEX or (if APR 125mg for acute: (MCP + DEX) or (APR + DEX))

Question 10

For DELAYED NV prophylaxis

- High AC =

Answer 10

High AC = NONE or (if APR 125mg for acute: DEX or APR)

Question 11

For DELAYED NV prophylaxis

- Carboplatin =

Answer 11

Carboplatin = NONE or (if APR 125mg for acute: APR)

Question 12

For DELAYED NV prophylaxis

- oxaliplatin or anthracycline or cyclophosphamide =

Answer 12

Oxaliplatin or anthracycline or cyclophosphamide = DEX can be considered

Question 13

For DELAYED NV prophylaxis

- moderate (other) / low/ minimal =

Answer 13

moderate (other) / low/ minimal = NO routine prophylaxis

Question 14

__________ do not drive delay CINV

Answer 14

5HT do not drive delay CINV

Question 15

Delayed CNIV

Aprepitant use for ____days

Answer 15

3days

Question 16

Delayed CNIV take _____________? (when)

Answer 16

30 min before treatment