Chlamydial infections Flashcards

1
Q

T/F Chlamydophila pneumoniae are obligate intracellular pathogens

A

T

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2
Q

Chlamydophila: Infectious form

A

Elementary body (EB)

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3
Q

Chlamydophila: Reproductive form

A

Reticulate body (RB)

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4
Q

T/F Ability to cause prolonged often subclinical infection is one of the major characteristics of chlamydiae

A

T

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5
Q

T/F Pneumonia caused by Chlamydophila is a classical atypical type with mild to moderate constitutional symptoms and CXR worse than clinical status of px

A

T

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6
Q

Optimum site for culture of C. pneumoniae

A

Posterior nasopharynx

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7
Q

Effective for eradication of C. pneumoinae from nasopharynx in ~80% of cases

A

Erythromycin, clarithromycin, azithromycin

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8
Q

Most important preventable cause of blindness in the world

A

Trachoma caused by chlamydia trachomatis

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9
Q

Criteria for trachoma

A

2 of 4: 1) Lymphoid follicles on upper tarsal conjunctivae 2) Typical conjunctival scarring 3) Vascular pannus 4) Limbal follicles

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10
Q

WHO recommends ___ for treatment of trachoma in children

A

Single-dose azithromycin

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11
Q

C. trachomatis is a major cause of what STDs

A

Epididymitis and nongonococcal urethritis

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12
Q

As many as ___% of men with gonorrhea may be co-infected with C. trachomatis

A

50

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13
Q

T/F Detection of C. trachomatis in vagina or rectum of a young child is an absolute evidence of sexual abuse

A

F, Perinatally acquired vaginal and rectal infection can persist for ≥3 years

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14
Q

Culture specimens for chlamydia detection

A

Urethral discharge in men and endocervical secretions in women

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15
Q

1st line treatment regimen recommended by CDC for uncomplicated C. trachomatis genital infection in men

A

Azith and Doxy

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16
Q

1st line treatment regimen recommended by CDC for uncomplicated C. trachomatis genital infection in nonpregnant women

A

Azith and Doxy

17
Q

Sex partners of patients with NGU should be treated if

A

1) They have had sexual contact with patient during the 60 days preceding onset of symptoms 2) MOST RECENT sexual partner even if last sexual contact was >60 days from onset of symptoms

18
Q

Approximately ___% of infants born to mothers with active untreated chlamydial infection develop clinical conjunctivitis

A

30-50

19
Q

Characteristic presentation of C. trachomatis infection: Onset

A

Between 1- 3 mos of age

20
Q

Characteristic presentation of C. trachomatis infection: Symptoms

A

Perisistent cough, tachypnea, ABSENCE OF FEVER

21
Q

Characteristic presentation of C. trachomatis infection: Signs

A

Rales, wheezing uncommon

22
Q

Helps to distinguish chlamydia pneumonia from RSV pneumonia

A

Absence of wheezing and fever

23
Q

Characteristic presentation of C. trachomatis infection: Distinct labb finding

A

Peripheral eosinophilia (>400cells/mm3)

24
Q

Characteristic presentation of C. trachomatis infection: Most consistent finding on chest radiograph

A

Hyperinflation, minimal interstitial or alveolar infiltrates

25
Q

Recommended treatment regimen for C. trachomatis conjunctivitis in infants

A

Erythromycin

26
Q

Recommended treatment regimen for C. trachomatis pneumonia in infants

A

Erythromycin

27
Q

CDC-recommended treatment of C. trachomatis infection in pregnant women

A

Azithromycin or Amoxicillin

28
Q

Lymphogranuloma venereum is a systemic STD caused by what organism

A

C. trachomatis

29
Q

LGV strains of C. trachomatis have a predilection for

A

Lymphoid tissue

30
Q

Stages of Lymphogranuloma Venereum

A

1st, Painless transient papules in the genitals (primary lesion; 2nd, UNILATERAL femoral or inguinal lymphadenitis with enlarging painful bbuboes; 3rd, genitoanorectal syndrome with rectovaginal fistulas, rectal strictures, and urethral destruction

31
Q

Recommended treatment for LGV

A

Doxy