clindamycin & metronidazole Flashcards Preview

Z A Pharm III > clindamycin & metronidazole > Flashcards

Flashcards in clindamycin & metronidazole Deck (10)
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1
Q

What is MOA clindamycin

A

inhibit protein synthesis (50S)

2
Q

What does clindamycin treat

A

anaerobes
Paracites
PCP

3
Q

How is clindamycin eliminated

A

bile

4
Q

What are common uses for clindamycin

A

anaerobic infections
acne
gardnerella vaginalis

5
Q

What are adverse effects of clindamycin

A

Diarrhea
hypersensitive
hepatic toxicity
pseudomembranous colitis

6
Q

what is MOA metronidazole

A

reactive metabolites that damage DNA

7
Q

What does clindamycin treat

A

G - anaerobes
G+ anaerobes
H pylori
protozoa

8
Q

What are common uses of metronidazole

A

DOC - C difficile colitis
peptic ulcer
vaginosis
chrohns

9
Q

What are types of metronidazole

A

Flagyl IV

- 15 over hr, then 7.5 over 1 hour q6h

10
Q

What are adverse effects of metronidazole

A
Neurologic effects
disulfiram w/ alcohol
GI upset
warfarin
hypersensitive