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Flashcards in Clinical Cases of Rash Deck (20)
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1
Q

Which condition is characterised by damage and infiltration of the basal layer of the epidermis?

A

Lichenoid eruptions

2
Q

Where on the body does pemphigus vulgaris commonly affect?

A

Scalp, face, axillae and groin

3
Q

Fine lace-like pattern on the surface of papules and on the buccal mucosa describes which characteristic sign?

A

Wickham’s striae

4
Q

Which age group does bullous pemphigoid affect?

A

Elderly

5
Q

What may present in the early stages of bullous pemphigoid?

A

Urticated itchy patches

6
Q

What is the main difference between rosacea and acne?

A

Rosacea does not involve comedones

7
Q

How is bullous pemphigoid treated?

A

Systemic steroids

(potentially oral tetraycline as adjunct)

8
Q

In which condition are steroids generally avoided as part of treatment?

A

Rosacea

9
Q

What will a skin biopsy show in a patient with pemphigus vulgaris?

A

Acantholysis

10
Q

Which investigations will be undertaken for either bullous pemphigoid or pemphigus vulgaris?

A

Indirect immunofluorescence

Skin biopsy (with direct immunofluorescence) - to detect IgG at the relevant skin boundary

11
Q

In which condition (pemphigus or pemphigoid) is mucosal involvement very common?

A

Pemphigus vulgaris

(rare in pemphigoid)

12
Q

When treating psoriasis, which medication is given alongside UVA treatment to make the skin temporarily sensitive to the UVA radiation?

A

Psoralen

13
Q

Which type of psoriasis is most common in young adults?

A

Guttate

14
Q

What is the preferred treatment for psoriasis?

A

Vitamin D analogues such as calcipotriol or calcitriol

15
Q

Which type of psoriasis can develop in acral regions and has acute presentation?

A

Palmoplantar

16
Q

How long must antibiotics be used before they can be considered ineffective in a patient with acne?

A

6 months

17
Q

Which acne treatment is keratolytic and antibacterial?

A

Benzoyl peroxide

18
Q

In very severe cases which treatment may be utilised?

A

Isotretinoin

19
Q

Which condition generally affects the volar wrists, forearms, shins and ankles?

A

Lichen planus

20
Q

What is described by

“The fact that psoriasis can develop in areas of trauma on the skin which are otherwise healthy”

A

Koebner phenomenon