Clinical Colon Cancer Lecture Flashcards Preview

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Flashcards in Clinical Colon Cancer Lecture Deck (13)
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1
Q

Chemo indicated in what stages of colon cancer

A

III and IV

II depending on invasion

2
Q

Serum CEA

A

used to follow cancer progression

test at diagnosis

3
Q

How many nodes should be sampled in colon cancer

A

at least 12

4
Q

What are high-risk stage II tumors

A

T4 type

invasive

5
Q
Tis
T1
T2
T3
T4
A
tumor penetration depth
Tis: in situ, only in mucosa
T1: submucosa invasion
T2: muscularis propria invasion
T3: through muscularis propria or subserosa
T4: other organs
6
Q

N0
N1
N2

A

node staging
N0: none
N1: 1-3 regional nodes
N2: 4+ regional nodes positive

7
Q

M0

M1

A

metastasis staging
M0: no mets
M1: distant mets

8
Q

Standard Tx of all colon cancer

chemo

A

5-FU

leucovorin

9
Q

Special chemo for stage III colon cancer

A

oxaliplatin

for some reason better outcomes

10
Q

In colonoscopies it’s most important to make it to this structure

A

visualize ileocecal area

11
Q

COX-2 inhibitors

A

for FAP

12
Q

ASA

A

prevent adenoma

13
Q

Cetuximab or panitumumab

use

A

in KRAS wildtype only