CNS Stimulant Flashcards Preview

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Flashcards in CNS Stimulant Deck (25)
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1
Q
Ritalin IR
Ritalin LA
Methylin
Concerta OROS
Metadate CD
  • MOA
  • SEs
  • DDIs
  • DOC
  • Indication:
  • Other stimulants
A

Methylphenidate

  • Ritalin IR: BID-TID b/4 meal. Max 20mg TID. Rapid abs
  • Ritalin LA: Can open n sprinkled on applesauce
  • Methylin: chewable tabs n oral sol’n
  • Concerta OROS: osmotic system
    Come in: 18, 27, 36, 54 mg ER
  • Metadate CD: 30% IR n 70% ER
  • MOA: Increase dopamine and NE. Stimulants
  • SEs: delayed onset of sleep, HA, decreased appetite = wt loss, slow growth, may exacerbate bipolar or psychotic condition. Heart problems pt, see cardiologist before.
    Tics (most common with patch)

DDIs:

  • MOA inhibitors
  • Foods high in tyramine content
  • TCAs
  • Antihypertensive agents
  • Sympathomimetics
  • Warfarin
  • Diamox: inc amphetamine [ ]

DOC

  • School age children: amphetamine/methylphenidate
  • Atomoxetine: use if fx object to tx with controlled sub
  • Alpha-2 adrenergic: helpful when used combined

Indication: ADHD

2
Q

Quillivant

  • Age
  • Dose
  • Indication
A

Methylphenidate XR oral sol’n

  • Age: > 6 y.o
  • Dose: 20mg PO QAM. Shake bottle for 10s. Require pharmacist to reconstitution.
  • Indication: ADHD
3
Q

Daytrana

  • Form
  • Frequency
  • Common SEs
  • Indication
A

Methylphenidate Patch

  • Transdermal patch. Worn daily 9hrs. Patch replaced QAM
  • Tics (most common with patch)
  • Indication: ADHD
4
Q

Focalin

  • Frequency: IR/ER
  • Indication
A

Dexmethylphenidate

  • IR: BID
  • ER: QD in AM. May sprinked over applesauce
  • Indication: ADHD
5
Q

Dexedrine

  • Indication
A

Dextroamphetamine

-Indication: Narcolepsy

6
Q

Vyvanse

  • CS
  • MOA
  • Indication
  • Dose
A

Lisdexamfetamine SR/IR

  • CS: II = Abuse. IV or intranasal is less abuse
  • MOA: stimulant
  • Indication: ADHD
  • Dose: 30mg PO QAM. Max 70mg/d
7
Q

Adderall IR/XR

  • Indication
  • Frequency: IR/XR
A

Dextroamphentamine + Amphetamine

  • Indication ADHD, Narcolepsy
  • IR: QD-BID given 1st thing in AM
  • XR: QD
8
Q

Provigil

  • Indication
  • Warnings
A

MODafinil

  • Indication: narcolepsy and shift work sleep disorder

Warnings

  • Psychiatric problems: anxiety, hallucinations, suicidal ideations
  • Serious allergic rxn (SJS): similar to lamictal
9
Q

Nuvigil

  • Indication
A

ARModafinil

  • Indication: Narcolepsy
10
Q

Strattera

  • MOA
  • Indication
  • Adv
  • Dose
  • Warning
A

Atomoxetine = not CS

  • MOA: selective NE reuptake inhibitor
  • Indication: ADHD
  • Adv: good for pets with anxiety, insomnia, or substance abuse disorders
  • Dose: max 100mg
  • Warning: severe liver injury and failure, priapism
11
Q

Intuniv
Tenex

  • MOA
  • Indication
  • Dose
  • SEs
A

Guanfacine = not CS

  • MOA: non-stimulant. Stimulate alpha-2a adrenoreceptors
  • Indication: ADHD (Tenex: tx high BP)
  • Dose: QD tx for children age 6-17 y.o
  • SEs: somnolence, HA, fatigue, abdominal pain.
12
Q

Kapvay

  • MOA
  • Indication
  • Dose
A

Clonidine ER Tab

  • MOA: Alpha 2 agonist
  • Indication: the 1st and only therapy approved for use with stimulant med for the tx of ADHD.
    Can use a mono therapy
  • Dose: start 0.1mg QD => titrate to BID
13
Q

Adipex-P

  • CS
  • Indication
A

Phentermine

  • CS IV
  • Indication: weight loss
14
Q

TENuate

  • CS
  • Indication
A

DIEThylpropion

  • CS IV
  • Indication: weight loss
15
Q

Didrex

  • CS
  • Indication
A

Benzphetamine

  • CS III
  • Indication: weight loss
16
Q

BONtril

  • CS
  • Indication
A

PhendiMETrazine

  • CS III
  • Indication: weight loss
17
Q

Xenical

  • MOA:
  • CS
  • Indication
  • Dose
  • Counseling points
  • SEs
A

Orlistat

  • MOA: gastric and pancreatic lipases inhibitors: inhibiting dietary fat absorption by 30%. Decrease TG and TC abs
  • CS: none
  • Indication: weight loss
  • Dose: 60-120 mg TID w/ or up to 1H after meals.
    Xenical (Rx): 120mg capsule
    => if a meal is missed or has no fat, skip the dose

SEs

  • GI: flatus with discharge. Oily stool w/ spotting. Fecal urgency and inconinence
  • Malabsorption of fat soluble carotenoid
  • Malabsorption of fat sol it: ADEK
18
Q

Belviq

  • MOA
  • CS Cat:
  • Indication
  • Dose
  • Caution
A

Lorcaserin

  • MOA: Selective 5-HT2C receptor agonist
  • CS IV
  • Indication: weight loss
  • Dose: 10mg BID
  • Caution: monitor for suicidal thought. Advise men to seek medical help for erection > 4H
19
Q

Qsymia

  • Indication
  • CS Cat
A

Phentermine + topiramate ER capsule

  • Indication: weight loss
  • CS IV => Phentamine
20
Q

Suprenza

  • Form
  • CS Cat
  • Indication
A

Phentermine

  • Form: ODT
  • CS Cat: CS IV
  • Indication: weight loss
21
Q

Regimex

  • Indication
  • CS Category
A

Benzphetamine

  • I: Weight loss
  • CS III
22
Q

Alli

  • Dose
A

Orlistat

  • (OTC): 60mg cap
23
Q

Contrave

  • Indication
A

Naltrexone and Bupropion

  • Indication: Weight loss
24
Q

Saxenda

A

Liraglutide

25
Q

Dextrostat

  • Indication
A

Dextroamphetamine

-Indication: Narcolepsy