Colon CA Flashcards Preview

Oncology > Colon CA > Flashcards

Flashcards in Colon CA Deck (9)
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1
Q

RFs for colon cancer?

A
Age
Adenomatous polyps
Family hx (FAP, HNPCC)
IBD
Previous cancer
Diet (high fat, low fibre)
Diabetes
2
Q

Primary prevention of colon CA?

A
Increase dietary fibre
Less animal fat and red meat
Decrease smoking and EtOH
Exercise
Weight loss if overweight
3
Q

Colon CA screening for people at average risk (>50, no FHx)?

A
One of:
FOBT every 2 years
Flex sig every 5 years
FOBT + Flex sig every 5 years
Double contrast barium enema every 5 years
Colonoscopy every 10 years
4
Q

Colon CA screening for people at above average risk?

A

HNPCC: genetic testing + cscope q2yrs at age 20

FAP: genetic testing + flex sig annually at age 10-12

Fam Hx of cancer/polyps: colonoscopy q5 at 40yo or 10 years earlier than youngest relative

5
Q

Signs and symptoms of colon CA?

A

Often asymptomatic
Hematochezia (L sided lesions)
Melena (R sided lesions)
Weakness, anemia, wt loss, palpable mass, obstruction

6
Q

Where does colon CA like to metastasize?

A

Lymph Nodes

Liver (most common) and lung via hematogenous spread

Ovary, Blumer’s shelf via peritoneal seeding

Intraluminal

7
Q

Investigations for colon CA?

A

Cscope or air contrast barium enema or flex sig to look for synchronous lesions

FOBT+ and microcytic anemia or bowel habit change = cscope

8
Q

Metastatic workup for colon CA?

A

CXR, abdo CT/S, bone scan, CT hear only if lesions suspected

9
Q

Treatment for colon CA?

A

Surgery in potentially curable or symptomatic cases

Radiotherapy and chemotherapy for patients with node positive disease and/or palliative