Commercial applications Flashcards Preview

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Flashcards in Commercial applications Deck (4)
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1

Describe the first transgenic fish

1985
Goldfish expressing human GH
Direct injection into the egg cytoplasm

2

Describe Canadian salmon

AFP (antifreeze protein) added to salmon to allow them to grow in all seasons in Canadian cold waters

3

Describe AquAdvantage salmon

GH
Growth rate affected rather than the final size
Less food required and reach market size 1 year earlier

4

Describe how human drugs can be made in sheep milk

AAT (antitrypsin) is treatment for cystic fibrosis
PI of AAT coupled with sheep β-lactoglobulin promoter which is tissue-specific to the mammary glands
Protein made in milk