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Flashcards in Dandruff Deck (14)
1

Dandruff is caused by

Malassezia feasting on sebum

2

Malassezia is

lipophilic yeast found in sebum rich areas of body

3

Malassezia contains _______ that _________

Lipases
Hydrolyze triglycerides--> sat. fatty acids

4

What penetrates the scalp and induces hypoproliferation

Leftover unsaturated fatty acids

5

Lack of synchronization between proliferation/differentiation in D/SD causes

irregular, highly invaginated corneocyte envelope structure

6

Penetration of SC by oleic acid results in

inflammatory response in susceptible persons
disturbs homeostasis
-->erratic cleavage of SC cells

7

4 sequential pathophysiological phases of D/SD

-Malassezia interaction w epidermis
-Initiation/Propagation of inflammation
-Disruption of proliferation/differentiation
-Physical/functional barrier disruption

8

Flaking is a result of _______ stage of dandruff

Proliferation/differentiation disruption

9

In P&G Study, oleic acid induced flaking in

dandruff-prone individuals only

10

Types of treatments for D/SD

-Keratinolytic agents
-Keratinization regulators
-antimicrobial agents

11

Salicylic acid and sulfur are ________ to treat dandruff

Keratinolytic

12

Zinc pyrithone is under the _______ category of dandruff treatment

Keratinization regulator

13

Selenium sulfides treat dandruff through _____ properties

antimicrobial

14

Dandruff prone individuals have

underlying barrier dysfunction allowing FUFA metabolites of sebum to easily penetrate the scalp