DD- DERM PBL Flashcards Preview

BL/DD USMLE and Basics > DD- DERM PBL > Flashcards

Flashcards in DD- DERM PBL Deck (19)
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1
Q

a connective-tissue disease that is characterized by inflammation of the muscles and the skin.

A

Dermatomyositis (DM)

2
Q

Dermatomyositis s/s

A

main symptoms include skin rash and symmetric proximal muscle weakness

3
Q

______ findings occur in dermatomyositis but not PM and are generally present at diagnosis.

A

Skin

4
Q

In DM, usually ____ presents first

A

skin symptoms (before muscle)

5
Q

DM is a ______ disorder

A

autoimmune

6
Q

______ (also in PM) refers to rough, cracked skin at the tips and lateral aspects of the fingers forming irregular dirty-appearing lines that resemble those seen in a laborer

A

Mechanic’s hands

7
Q

a diffuse, flat, erythematous lesion over the back and shoulders or in a “V” over the posterior neck and back or neck and upper chest, which worsens with UV light

A

V sign or Shawl Sign, present in DM

8
Q

Erythematousraised papules overlying the metacarpal and interphalangeal joints

A

Gottron’s papules

9
Q

facial erythema with facial edema and scale represents a recent disease flare in an adult patient with dermatomyositis.

A

Malar and facial erythema

10
Q

DM is likely triggered by

A

autoimmune

malignancy , infection, drug related

11
Q

DM age?

A

Kids and adults

12
Q

Systemic DM

A

myopathy
pulm disease
malignancy
calcinosis

13
Q

High blood levels of _______ are often present in dermatomyositis or polymyositis

A

Creatine kinase (CPK)

14
Q

Confluent macular erythema confined to the upper eyelid, with associated periorbital edema.

A

Heliotrope

present in DM

15
Q

Lupus rash will spare the ______, DM will not

A

knuckles

DM is also itchy

16
Q

____ infiltrates in DM

A

CD4 T cells

17
Q

_______ infiltrates in PM

A

CD8 T cells

18
Q

Connective Tissue disorders

A
  • scleroderma
  • DM
  • Lupus
19
Q

SLE will have ______ and DM will have shawl sign in a photosens distribution

A

Annular lesions