Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PRIYA MSK BASICS > DMARDS > Flashcards

DMARDS Flashcards

1
Q

which proteins are used to measured monthyl to assess effectieness of DMARDS

A

serum acute phase proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how does methotrexate work

A

folate antagonists (binds dihydrofolate reductase)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

side effects of methotrexate

A

pneumonitis - pulmonary fibrosis/ cough
hepatoxicity
leucopenia, thrombocytopenia, GI upset
teatrogenic (both males and females)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what type of drug is sulfasalazine

A

aminosalicylate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

side effects of sulfalasaline

A 
temporay oligospermia (sperm cells in semen) 
depression
hepatitis
GI upset 
ulcers / rash
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how do hydroxycholoquine work

A

antimalarial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are the side effects of hydrocycholoquine

A

adverse retinopathy
corneal depositis
hamatolytic anaemia
GI upset

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

how does leflunamide work

A

inhibts dihydroorolate dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

side effect of SE

A

ILD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

side effects of gold

A

proteinuria + peripheral neuropathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

how does penicillamine work

A

chelating agent (wilsons disease)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

side effects of penicllamine

A 
rash 
aggridation of mysathenia gravis 
goodpasture syndrome
proteinuria
glomerulonephritis 
anaemia 
GI upset
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

side effects of axathioprine

A 
marrow suppression 
infection
nephrotoxcitiy
acute pancreatitis 
GI upset 
teatrogenic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

how does ciclosporin work

A

blocks cytotoxic T cell activation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how does prednisolone work

A

binds glucocorticoid receptor (alpha / beta)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what does prednisolone do

A

salt / water retention
increased glucneogenesis
increased hepatic glycogen depostion
increased protein breakdown

17
Q

side effects of prednisolone

A 
OP
DM 
hypertension
caracts
glaucoma
18
Q

risk of anti TNF drugs

A

reactivation of TB

skin cancer

19
Q

contraindications for anti-tnf drugs

A

HF

pulmonary fibrosis

20
Q

which drug casues demelination

A

entanercept

PRIYA MSK BASICS (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions