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Paramedic Drugs Week 19 > Dopamine > Flashcards

Flashcards in Dopamine Deck (14)
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1
Q

Dopamine

Class

A

Sympathomimetic, inotropic agent

2
Q

Dopamine

Mechanism of Action

A

Immediate metabolic precursor to norepinephrine. Increases systemic vascular resistance. Causes peripheral vasoconstriction, but dilates renal vasculature at low doses. Increases myocardial contractility and stroke volume.

3
Q

Dopamine

Indication

A

Cardiogenic, septic or spinal shock, hypotension with low cardiac output states, and distributive shock.

4
Q

Dopamine

Contraindications

A

Hypovolemic shock, pheochromocytoma, tachyarrhythmias, V-fib.

5
Q

Dopamine

Adverse Reactions

A

Cardiac arrhythmias, hypertension, increased myocardial oxygen demand; extravasation may cause tissue necrosis.

6
Q

Dopamine

Drug Interactions

A

Drug interactions: Incompatible with alkaline solutions. MAOIs will enhance the effects of dopamine. Bretylium may potentiate effect of dopamine. Beta- blockers may antagonize the effects of dopamine. When administered with phenytoin; may cause hypotension, bradycardia, and seizures.

7
Q

Dopamine

Adult Dosage

A

IV infusion at 2 – 20 mcg/kg/min titrated to effect

8
Q

Dopamine

Pediatric Dose

A

2 – 20 mcg/kg/min titrated to effect

9
Q

Dopamine

Onset

A

1 – 4 minutes

10
Q

Dopamine

Peak Effect

A

5 – 10 minutes

11
Q

Dopamine

Duration

A

Effects stop almost immediately after infusion is stopped

12
Q

Dopamine
Special Consideration
2-5mcg/kg/min

A

2 – 5 mcg/kg/min: dilates vessels in kidneys; increased urine output.

13
Q

Dopamine
Special Consideration
5-10mcg/kg/min

A

5 – 10 mcg/kg/min: increased heart rate (beta effects)

14
Q

Dopamine

10-20mcg/kg/min

A

10 – 20 mcg/kg/min: primarily vasoconstriction (alpha effects)