Downing: Placental Histology Flashcards Preview

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Flashcards in Downing: Placental Histology Deck (21)
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1
Q

On what day does the trophoblast meet the prepared secretory phase of the endometrium?

A

Day 6, ‘it tacks 6 days to stick’

2
Q

Day 7: What to cytotrophoblast give rise to? Are they mitotically active?

A

syncytiotrophoblast, a true mass of cells with no boundaries that are highly aggressive and erosive into the endometrial surface

3
Q

What contains maternal and glandular secretions around Day 9?

A

Lacunar networks! syncytium keeps expanding into the glands and arteries.

4
Q

Day 13: what does ‘forming the villi of the placenta’ consist of?

A

movement of cytotrophoblasts towards the interface between somatic mesoderm and the syncytiotrophoblast

5
Q

T or F: primary villi consist only of trophoblast (syncytiotrophoblast and cytotrophoblast)

A

T. no extraembryonic mesoderm yet!

6
Q

What are the three layers of the secondary villi?

A

syncytiotrophoblast (outer), cytotrophoblast (middle), mesodermal core (inner)

7
Q

What kind of villi have a cytotrophoblastic shell formation?

A

ANCHORING. invasion of cytotrophoblast through syncytiotrophoblast and it makes direct contact with decidual cells

8
Q

what does the tertiary villi consist of?

A

differentiation of blood vessels in the mesodermal core of secondary villus.

9
Q

in which villi stage do you get anastomosis of villar blood vessels with fetal circulation?

A

tertiary villi!

10
Q

what villi starts to have a CORE OF MESODERM?

A

secondary villi

11
Q

______ is the transformation of endometrial stromal cells

A

Decidual reaction. Swell due to glycogen and lipid accumulation. transformation spreads throughout superficial layers of endometrium

12
Q

what is the decidua basalis?

A

maternal portion of placenta, site of decidual reaction and most extensive villar invasion

13
Q

where is the decidua capsularis located?

A

between conceptus and uterine lumen

14
Q

_____ is the remainder of the endometrium?

A

decidua parietalis

15
Q

what is the fetal placental circulation?

A

umbilical arteries -> chorionic arteries -> villar caps -> chorionic veins -> umbilical vein

16
Q

What is the maternal circulation of the placenta?

A

spiral arteries -> intervillous space -> endometrial veins

17
Q

after how many weeks does the cytotrophoblast progressively disappears and connective tissue thins? what does the barrier then become?

A

20 wks. syncytial trophoblast, basal laminae, fetal capillaries.

18
Q

What organisms are in TORCH?

A

Toxoplasmosis, other infections (hep B, cox, syphillis, VZV, HIV, parvovirus b19), rubella, CMV, HSV-2

19
Q

what hormone maintains corpus luteum and its production of progesterone and estrogen in the first trimester?

A

Human chorionic gonadotropin (hCG)

20
Q

what can be measured within 6 days of fertilization in a urine test?

A

hCG

21
Q

what is produced by the decidua cells and helps to SOFTEN the cervix just prior to parturition?

A

RELAXIN