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Flashcards in Drug allergies and ADRs Deck (12)
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1
Q

What is a type A reaction

A

dose-dependent and predicatble based on the drugs pharmacology

2
Q

What is a type B reaction

A

not dose-dependent are unrelated to the pharmacologic actions and can be influenced by patient-specific factors

3
Q

what is a type 1 allergic reaction

A

immediate within 15-30 minutes

4
Q

What is a type 2 drug allergy

A

reacts minutes to hours

5
Q

What is a type 3 drug allergy

A

occurs 3-10 hours after exposure

6
Q

what is a type 4 drug allergy

A

delayed hypersensitvity can take from 48 hours to weeks to show up

7
Q

what is a boxed warning

A

indicates a risk of death or permanent disability

8
Q

key drugs associated with photosensitivity

A
amiodarone
diuretics-loop and thiazide
mtx
oral and topical retinoids
quinolones
st john's wort
sulfa
tacrolimus
tetracyclines
voriconazole
9
Q

key drugs associated with TTP (thrombotic thrombocytopenia purpura)

A

clopidogrel

sulfamethoxazole

10
Q

what drugs to avoid in sulfa allergy

A
sulfasalzaine
sulfadiazine
sulfisoxazole
thiazide diuretics
loop diureteics
acetazolamide
zonisamide
celecoxib
cedofovir
11
Q

drugs to avoid with a peanut or soy allergy

A

clevidpine
propofol
progesterone

12
Q

drugs to avoid with an egg allergy

A

clevidipine
propofol
yellow fever vaccine