Drug Eruptions and Photodermatology

Question 1

What is this?

Answer 1

Exanthematous Drug Eruption

Question 2

What type of hypersensivity reaction is this?

Answer 2

T cell mediated type IV hypersensitvity reaction

Question 3

What is common for the onset of a Type IV hypersensitivity exanthematous drug eruption?

Answer 3

Onset is 4-21 days after first drug

Will be symetrical

Question 4

What are the characteristics of a urticarial drug eruption?

Answer 4

IgE mediated Type 1 hypersensitivity

Quick onset

Question 5

What is this?

Answer 5

Fixed drug eruption

Question 6

What is this?

Answer 6

Steven Johnson syndrome and Toxic epidermal necrolysis

Question 7

What are phototoxic cutaneous drug reactions?

Answer 7

Non immunolgical mediated skin reactions caused by photoreactive drugs reaction with light

Question 8

What are porphyrias?

Answer 8

A group of inherited metabolic disorders

Question 9

What are the four main groups of porphyrias?

Answer 9

Phototoxic skin porphyrias

Blistering and fragility skin porphyrias

Acute attack porphyrias

Sever congenital porphyrias