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Nutrition Support Certification Exam 2013 > Drug-Nutrient Interactions > Flashcards

Drug-Nutrient Interactions Flashcards

1
Q

Ampho B

A

dec Ca+,Vit D, folic acid, zinc

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2
Q

Dilantin

A

Dec Vit D, folic acid

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3
Q

ABX

A

Dec Vit K

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4
Q

Heparin and coumadin

A

Avoid Large doses Vit C

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5
Q

Zinc decreases with

A

albumin, Vit A, infection, worsens hepatic dysfunction, dec resp fx, muscle fx and glucose intolerance

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6
Q

Add zinc in what diagnosis

A

TBI, hypermetabolism, GI losses, wounds

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7
Q

Inc CRP does what to zinc levels

A

dec 50%

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8
Q

Decreased Copper with what food/vits

A

phytates (whole grains, legumes, nuts/seeds), fiber, zinc, Fe, large doses Vit C

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9
Q

Dec Vit D with

A

Decreased Copper in malnourished

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10
Q

Increased zinc when

A

decreased Copper

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11
Q

Diarrhea depletes

A

K+ & Magnesium

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12
Q

Prolonged diarrhea depletes

A

Selenium (SBS)

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13
Q

Low Magnesium- what do you decrease in diet

A

fat binds to Magnesium and increases stool output

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14
Q

Neomycin- (ABX) does what to GI

A

partially villous atrophy and steatthorea

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15
Q

Cholestyramine causes what vitamin deficiency

A

def in ADEK

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16
Q

ACE

A

In Ca+, K+, Na and Dec PO4

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17
Q

Sulfasalazine (UC, RA)

A

Dec body stores folic acid, B12 with large doses long term

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18
Q

Dilantin

A

dec absorption of folic acid, Vit D, Vit K in fetus

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19
Q

Valproic Acid

A

carnitine

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20
Q

ABX aminoglycosides-tobra, gent

A

Dec Mg & K+= hearing loss

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21
Q

Cyclosporine

A

no grapefruit

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22
Q

Albuterol (beta antagonists)

A

Dec K+

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23
Q

Loop diuretics (lasix)

A

Dec Mg, K, Ca

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24
Q

Thiazide diuretics (Hctz)

A

decreased urine excretion of Ca

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25
Q

Jtube drugs not absorbed

A

carbomazepine (anti-seizure), cipro, Ca, Mg, antacid, Fe, coumadin hold 2 hr before/after

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26
Q

MAOI

A

no tyramine (aged cheese, salami, sauerkraut, soy, tap beer, wine, vermouth)

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27
Q

Chemo (patins)

A

loss Mg, Dec Ca-not respond to suppl

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28
Q

Decrease FAt soluble vits

A

statins, mineral oil laxatives

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29
Q

High protein

A

inc excretion of Calcium

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30
Q

Flagyl (metronidazole)

A

avoid ETOH and exilir

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31
Q

Ring worm med (Griseofulvin)

A

No ketogenic diet

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32
Q

Fatty foods with Gemfibozil

A

decreases activity

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33
Q

Lithium

A

HIgh salt=lithium excreted, Low salt= lithium toxic

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34
Q

Digoxin

A

No fiber TF- watch s/s, no licorice which incrases BP naturally

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35
Q

Zantac

A

Dec absorption Fe

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36
Q

Average Vit K in diet

A

90-118 mcg/day (<100mcg per 1000 cals)

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37
Q

Levothyroxine (sythroid) decreased absorption with what type of protein

A

soy

38
Q

Which mins have high osmolality and must be spaced out

A

K, PO4, Mg

39
Q

High osmolar diuretic that must be diluted

A

lasix= 3900 with 49% sorbitol

40
Q

ranitidine in PN with 12 hr cycle

A

another does for additional 12 hrs off PN

41
Q

Iron Dextran IV

A

no lipid in PN, over 18 hrs

42
Q

Reglan (metroclopramide) helps

A

nausea with Hyperemesis

43
Q

Ginger/B6 helps

A

nausea with Hyperemesis

44
Q

triamterene

A

K+ sparing diuretic

45
Q

ADH released when what happens to serum

A

Inc osmolality

46
Q

Large doses Vit C, Avoid with these meds/vits

A

heparin, coumadin and Copper

47
Q

Low Mg, decrease this in diet

A

fat- it binds with Mg to make it lower

48
Q

HD- lose these vits

A

water soluble B and Fe

49
Q

Inflammatory mediators include

A

cytokines, TNF, interleuken-1

50
Q

Microcytic, hypochromic anemia

A

Fe, Copper

51
Q

Macrocytic anemia

A

Folic acid

52
Q

Megaloblastic anemia

A

B12, Folic acid

53
Q

Micrcytic

A

B6

54
Q

@ risk of B6 deficiency

A

HD, elderly, steroids, anticonvulsants, ETOH

55
Q

Decreased Vit D s/s

A

muscle weakness, High BP, HL

56
Q

Fe absorbed where?

A

proximal jejunum

57
Q

Hold TF with these meds

A

theophylline, cipro, dilantin, coumadin

58
Q

metheotrexate can bind with this vit

A

folate

59
Q

Decreased absorption of Folic acid with these factors

A

impaired bile, change jejunal pH

60
Q

Meds that dec absorption of Folic acid

A

dilantin, ampho B, sulfasalazine, choestyramine, PD dialysis

61
Q

citrate, gluconate, lactate acetate are

A

bicarbs

62
Q

SIADH

A

euvolemia, total body inc, conc urine

63
Q

Inc ADH

A

conc urine

64
Q

Independent predictor for m/m in critically ill

A

alb < 2.6

65
Q

Starvation

A

dec Gluc, ketosis, lipolysis

66
Q

Stress Malnutrition

A

Hypermetabolism, Inc Gluc, lipolysis

67
Q

Malnurition is what wt loss criteria

A

10% wt loss UBW x 6 months, equal or greater than 5% wt loss x 1 month

68
Q

Jtube feeds, check this vit level

A

Fe

69
Q

Overfeeding

A

resp acidosis

70
Q

TF syndrome

A

Hi BUN/creat, Inc Na, dehydration s/t HI PRO/low fluid

71
Q

Hypocaloric with Obese

A

BMI > 30, 22 cals/kg

72
Q

GFR for ESRD

A

< 15cc/min or 1.73m2

73
Q

PRO for PD Dialysis

A

1.2-1.3g/kg/d

74
Q

CF @ risk what vit def

A

fat soluble d/t panc insufficiency.

75
Q

Essential Fatty Acid sources

A

veg oils- canola, flaxseed, walnut, fish

76
Q

SB overgrowth

A

D lactic acidosis

77
Q

Octreotide

A

refractory diarrhea

78
Q

SB 150-200 cm

A

significant losses

79
Q

WHO oral rehydration soln

A

CHO 40g, NA 90g, K 20, Osmo 311

80
Q

Normal length small bowel

A

600 cm

81
Q

Normal length colon

A

150

82
Q

SBS without colon

A

add salt, high fluid/Na output, no simple sugars, isotonic/high Na ORS

83
Q

Inflammatory hormones

A

epinephrine, glucogan, cortisol

84
Q

Body process with Acute Response Phase

A

glucogenolysis, gluconeogenesis, liplysis, proteolysis

85
Q

SBS with colon

A

Intol high fat, hypotonic fluid, bacterial overgrowth, oxalate kidney stones, unabsorbed bile salts damage colon–secretory diarrhea.

86
Q

Diet for SBS with colon

A

small freq meals, low fat, complex CHO, limit simple sugars, MCT, EFA, soluble fiber, low oxalates, sip ORS

87
Q

Diet for SBS without colon

A

small freq meals, avoid low cals/high fiber, restrict simple sugars, add salt, sip isotonic/high Na ORS,suppl lytes with po /IV, antiperistaltic agents a meals, H2 blockers, PPI

88
Q

Most widely tool to measure generic healthy status

A

SF 36

89
Q

Fat increases blood flow to

A

GI

90
Q

Lower threshold with initiation of PN in this population

A

elderly

91
Q

GAstric Bypass supple these vits

A

B12, B1, zinc, copper

Nutrition Support Certification Exam 2013 (11 decks)

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