Drugs for Psychosis from Dr. Smith Flashcards Preview

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Flashcards in Drugs for Psychosis from Dr. Smith Deck (11)
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1
Q

Schizophrenia and psychosis is linked to excess _______ in the brain

Therefore ________ antagonism is the main MOA of all antipsychotic meds

A

dopamine

2
Q

What is our high-potency, typical, anti-psychotic?

A

Haloperidol

3
Q

muscle spasms of various muscle groups and prolonged muscular contractions, usually of the head and neck

A

Acute dystoniaas

4
Q

How do we treat acute dystonia?

A

IM anticholinergic agents

5
Q

Late-onset EPS. Characterized by choreoathetosis and other involuntary sucking and smacking of lips and mouth

A

Tardive dyskinesia

6
Q

Hyperpyrexia, extrapyramidal rigidity, severe ANS dysfunction, myoglobinuria, lead-pipe rigidity, and sometimes death

A

Neuroleptic Malignant Syndrome

7
Q

Low potency typicals often have a high rate of _____ side effects but a low rate of ______. Conversely, high-potency typicals often have a low rate of _______ side effects but a high rate of _______.

A

Ach, EPS

Ach, EPS

8
Q

Side effects of 2nd generation anti-psychotics – the “pine” drugs specifically

A

Metabolic stuff

Obesity, hyperglycemia, and hyperlipidemia

9
Q

Major side effect from Olanazpine [Zyprexa]?

A

Weight gain

10
Q

“__________ is the most effective anti-psychotic drug, but it should be reserved for refractory disease because of its potential for serious hematologic toxicity and strict monitoring requirements.”

A

Clozapine

11
Q

The “-done” drugs cause what type of side effects?

A

Neurological