DTP Ceftriaxone Flashcards

1
Q

Ceftriaxone drug class

A

Antibiotic

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2
Q

Pharmacology of ceftriaxone

A

Ceftriaxone is a third generation cephalosporin antibiotic used in the treatment of meningococcal septicaemia

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3
Q

Indications for ceftriaxone

A

Suspected meningococcal septicaemia with non blanching petechial or purpuric rash

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4
Q

Contraindications for ceftriaxone

A

KSAR to cephalosporin drug

Known anaphylaxis or severe allergic reaction to penicillin based antibiotics

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5
Q

Precautions of ceftriaxone

A

Nil

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6
Q

Side effects of ceftriaxone

A
  1. Nausea / vomiting

2. Intense pain at site of injection

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7
Q

Presentation of ceftriaxone

A

1 g vial of powder

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8
Q

Onset, duration and half life of ceftriaxone

A

Onset = 30 secs IVI 60 secs IMI, duration = 5-10 mins, half life = 2 mins

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9
Q

Schedule for ceftriaxone

A

S4 restricted drugs

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10
Q

Adult doses for ceftriaxone

A

IMI 1 g mixed with 3.6 mls of water for injection

IVI 1 g mixed with 9.6 mls of water for injection

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11
Q

Paediatric doses for ceftriaxone

A

IMI all doses mixed with 3.6 mls of water for injection, 50 mg / kg = 0-5 kg 250mg, 5-10kg 500 mg, 10-15 kg 750 mg, >20 kg 1gm
IVI all doses mixed with 9.6 mls of water for injection, 50 mg / kg = 0-5 kg 250mg, 5-10kg 500 mg, 10-15 kg 750 mg, >20 kg 1gm

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12
Q

Special notes for ceftriaxone

A

All cannulae should be flushed with saline following administration

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