DTP Salbutamol (Ventolin) Flashcards
1
Q
Salbutamol drug class
A
Beta adrenergic agonist
2
Q
Pharmacology of salbutamol
A
- a direct acting sympathomimetic
- mainly affects the b2 adrenoreceptors
- primarily acts as a bronchodilator
- also has inotropic and chrontropic actions
- also lowers serum potassium levels by it’s direct stimulation of the sodium / potassium pumps drawing potassium into the cells.
3
Q
Metabolism of salbutamol
A
By the liver excreted by the kidneys
4
Q
Indications for salbutamol
A
- Bronchospasm
2. Suspected hyperkalaemia with QRS widening and / or av disassociation
5
Q
Contraindications of salbutamol
A
- KSAR
2. Pts <2 yrs
6
Q
Precautions of salbutamol
A
- Acute pulmonary oedema
2. Ischaemic heart disease
7
Q
Side effects of salbutamol
A
- Anxiety
- Tacharrythmias
- Muscle tremors
- Hypokalaemia
- Metabolic acidosis
8
Q
Presentation of salbutamol
A
5 mg in 2.5 ml nebule
500 mcg in 1 ml ampoule
9
Q
Onset of salbutamol
A
2-5 mins neb,
1-3 mins IV
9
Q
Duration of Salbutamol
A
16-60min neb
10-20min IV
10
Q
Half-life of Salbutamol
A
1.6 hrs
11
Q
Schedule of salbutamol
A
S4 restricted drugs
12
Q
Special notes for salbutamol
A
- Indifferent preparations of salbutamol are used for the IV and nebulised routes, do not mix
- NEB w/ 6-8L/min
- COPD pts = 6L/min
- Discard foil contents three months from opening
13
Q
Adult dose of salbutamol for Bronchospasm
A
5mg NEB
repeated prn
NMD
14
Q
Paediatric dose of Salbutamol for Bronchospasm
A
> 2 yo
5mg NEB
repeated PRN
NMD
