Dyslipidemias Flashcards Preview

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Flashcards in Dyslipidemias Deck (11)
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1
Q

Type I Hyperlipoproteinemia

A
Hypertriglyceridemia
Eruptive Xanthomas
Deficiency of LPL, ApoC-II
Reduced LDL and HDL levels
No inc risk CAD
2
Q

Type II Hyperlipoproteinemia

A

Tendinous, Tuberoeruptive, Tuberous, Plane (xanthelasma, intertrig, web spaces)
LDL receptor defect, decreased LDL clearance
Defective apo B-100
Inc degradation of LDL receptor bc mutation in PCSK9
Athlerosclerosis of Cor Arts

3
Q

Type III Hyperlipoproteinemia

A

Apo E abnormalitity
Hypercholesterol, hypertriglyceride
Tuberoeruptive, tuberous, plane (palmar creases), Tendinous atheroscler of periph and CAD

4
Q

Type IV Hyperlipoproteinemia

A

Elevated production of VLDL
Eruptive Xanthomas
Assoc with Type 2 DM, Obesity, alcohol

5
Q

Type V Hyperlipoproteinemia

A

Elevated chylomicrons and VLDLs
Decreased LDL and HDL. HyperTG
Eruptive Xanthomas, Assoc with Diabetes

6
Q

Familial LPL deficiency, Familial hyperchylomicronemia

A

Type I ApoCII and LPL def

7
Q

Familial hyperchol or familal def apoB-100

A

LDL receptor def

Type II

8
Q

Familial dysbetalipoproteinemia, ApoE def

A

Type III

9
Q

Endogenous familial HyperTG

A

Type IV–DM2, etoh, obesity. Eruptive

10
Q

Eruptive Xanthomas

A

Type I, IV, V

11
Q

Tendinous, Tuberous, Plane

A

Type II-Plane intertrig, web spaces, xanthelasma

TYpe III–Plane palmar crease