Endocrine Physiology Flashcards Preview

GFG Physiology > Endocrine Physiology > Flashcards

Flashcards in Endocrine Physiology Deck (9)
Loading flashcards...
1
Q

Which of the following is true regarding thyroid hormones?

a. acts on nuclear receptors
b. utilizes G proteins as 2nd messengers
c. activates preformed enzymes
d. A and B
e. A and C

A

A. acts on nuclear receptors

Thyroid hormones are protein hormones which act like lipid hormones in terms of binding, mechanism of action, and effect on enzyme activation / synthesis.

They traverse the membrane to act on nuclear receptors and promote synthesize of new hormones.

Handout page 94

2
Q

Enumerate 3 examples of positive feedback in endocrine organs.

A

oxytocin surge during delivery
oxytocin surge during lactation
LH and FSH surge during ovulation

3
Q

True or False

Binding of GDP to the alpha subunit of the G protein complex inactivates the protein.

A

True.

Binding to GTP activates the protein.

4
Q

Recite the cascade of events in the cyclic AMP messenger system.

A
GTP binds to alpha subunit of G protein
G protein activates adenylate cyclase
AC converts ATP to cyclic AMP
cAMP activates protein kinase A
PKA activates target enzymes

Alpha > AC > ATP > cAMP > PKA

5
Q

The IP3/DAG messenger system is used by all hypothalamic hormones EXCEPT:

a. GHRH
b. CRH
c. GnRH
d. TRH
e. NOTA

A

B. CRH

6
Q

The neurohypophysis produces which hormone/s?

a. TSH
b. ACTH
c. ADH
d. oxytocin
e. A and B
f. C and D
g. NOTA

A

G. none

The neurohypophysis / posterior pituitary does not produce any hormone. It just stores and secretes ADH and OXYTOCIN produces in the HYPOTHALAMUS.

7
Q

Which enzyme promotes cell growth and division on the target tissues or organ?

a. somatotropin
b. somatostatin
c. somatomedin
d. somatoflavin
e. NOTA

A

C. somatomedin

8
Q

Enumerate at least 3 protein products derived from POMC.

A
MSH
ACTH
beta lipotropin
beta endorphin
met enkephalin
9
Q

Which of the following is NOT an effect of growth hormone.

a. increase plasma glucose
b. increase protein synthesis
c. increase lipolysis
d. increase collagen synthesis
e. NOTA

A

E. none

All are actions of growth hormone. It has both ANABOLIC and CATABOLIC effects.

Handout page 96