Endocrinology

Question 1

Definitive diagnosis for Hypopituitarism

Answer 1

Absent or low levels of GH in response to stimulation

Question 2

Normal range for height; over time it starts falling off the height curve

Answer 2

Pathological short stature

Question 3

Normal range for height; normal final adult height is reached but growth spurt and puberty is delayed

Answer 3

Constitutional Short Stature

Question 4

Stays parallel to the growth Curve

Answer 4

Familial Short Stature

Question 5

Parallel to the growth curve but is much more marked

Answer 5

Prenatal Short Stature

Question 6

Overproduction of GH with open epiphyses

Answer 6

Gigantism

Question 7

Overproduction of GH with closed epiphyses

Answer 7

Acromegaly

Question 8

Diagnosis of GH excess

Answer 8

Serum Somatomedin C (IGF-I)

Question 9

Cardinal features of Diabetes Insipidus

Answer 9

Polyuria

Polydipsia

Question 10

Principal regulator of tonicity

Secreted from the posterior pituitary

Synthesized in the paraventicular and supraoptic nuclei of the hypothalamus

Has both antidiuretic and vasopressor

Answer 10

Vasopressin

Question 11

Vasopressin deficiency

Answer 11

Central Diabetes Insipidus

Question 12

Vasopressin insensitivity

Answer 12

Nephrogenic Diabetes Insipidus

Question 13

How to distinguish Central VS Nephrogenic DI

Answer 13

Water deprivation test and ADH administration

Question 14

Serum osmolality >300 mOsm/kg

Urine osmolality <300 mOsm/kg

Answer 14

Diabetes Insipidus

Question 15

Precocious puberty in boys and girls

Answer 15

Boys: 9y/o
Girls: 8y/o

Question 16

Treatment for true precocious puberty

Answer 16

Leuprolide Acetate