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Flashcards in Epigenetics crash course Deck (5)
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1
Q

How can histones be covalently modified?

A
  • methylation
  • acetylation
  • phosphorylation
  • ubiquitilation
2
Q

Acetylation of histone lysine residues

A

increases transcription (DNA is not as tightly bound anymore)

3
Q

Methylation of H3K4

A

promotes activation

4
Q

Methylation of H3K9

A

promotes repression

5
Q

Where does DNA methylation often occur?

A

At CpG islands